New drug YL201 enters human trials for Hard-to-Treat cancers
NCT ID NCT05434234
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests a new drug called YL201 in people with advanced solid tumors that have stopped responding to standard treatments. The trial has two parts: first, finding a safe dose, then testing that dose in more patients with specific cancer types. YL201 is given by IV every three weeks, sometimes combined with another cancer drug called atezolizumab. The goal is to see if it is safe and can shrink tumors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
YL201 (a drug given by IV infusion every 3 weeks, alone or with atezolizumab)
What this could lead to
If successful, this could lead to a new treatment option for people with advanced solid tumors that have not responded to other therapies.
What could go wrong
This is an early, first-in-human study, so safety and effectiveness are not yet known. The drug may cause side effects or not shrink tumors as hoped.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED SOLID TUMOR are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
001
RECRUITINGLa Jolla, California, 92093-0698, United States
Contact
-
002
RECRUITINGFair Oaks, California, 95628, United States
Contact
-
003
RECRUITINGLone Tree, Colorado, 80124, United States
Contact
-
004
RECRUITINGWashington D.C., District of Columbia, 20007, United States
Contact
-
005
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
-
006
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact
-
007
RECRUITINGDetroit, Michigan, 48292, United States
Contact
-
008
RECRUITINGSt Louis, Missouri, 63110, United States
Contact
-
009
RECRUITINGSanta Fe, New Mexico, 87505-699, United States
Contact
-
010
RECRUITINGNew York, New York, 10029, United States
Contact
-
011
RECRUITINGChapel Hill, North Carolina, 27514, United States
Contact
-
012
RECRUITINGNashville, Tennessee, 37203, United States
Contact
-
013
RECRUITINGSan Antonio, Texas, 78229, United States
Contact
-
014
RECRUITINGHouston, Texas, 77030, United States
Contact
-
015
RECRUITINGIrving, Texas, 75039, United States
Contact
-
016
RECRUITINGTyler, Texas, 75701, United States
Contact
-
017
RECRUITINGFairfax, Virginia, 22031, United States
Contact
-
018
RECRUITINGSpokane, Washington, 99208, United States
Contact
-
019
RECRUITINGTacoma, Washington, 98405, United States
Contact
-
020
RECRUITINGEdmonton, Alberta, T6G 1Z2, Canada
Contact
-
021
RECRUITINGKelowna, British Columbia, V1Y 1E2, Canada
Contact
-
022
RECRUITINGBrampton, Ontario, L6R 3J7, Canada
Contact
-
023
RECRUITINGToronto, Ontario, M5G 2C4, Canada
Contact
-
024
COMPLETEDGuangzhou, Guangdong, 510000, China
-
025
COMPLETEDZhengzhou, Henan, 450003, China
-
026
RECRUITINGBordeaux, 33000, France
Contact
-
027
RECRUITINGDijon, 21000, France
Contact
-
028
RECRUITINGMarseille, 13005, France
Contact
-
029
NOT_YET_RECRUITINGNantes, 44093, France
Contact
-
030
NOT_YET_RECRUITINGParis, 75248, France
Contact
-
031
RECRUITINGPoitiers, 86021, France
Contact
-
032
NOT_YET_RECRUITINGSaint-Herblain, 44800, France
Contact
-
033
RECRUITINGSuresnes, 92150, France
Contact
-
034
RECRUITINGBarcelona, Barcelona, 08023, Spain
Contact
-
035
RECRUITINGBarcelona, Barcelona, 08025, Spain
Contact
-
036
RECRUITINGMadrid, Madrid, 28050, Spain
Contact
-
037
RECRUITINGMadrid, Madrid, 28034, Spain
Contact
-
038
RECRUITINGMoncloa-Aravaca, Madrid, 28040, Spain
Contact
-
039
NOT_YET_RECRUITINGLeganés, Madrid, 28911, Spain
Contact
-
040
RECRUITINGPamplona, Navarre, 31008, Spain
Contact
-
041
RECRUITINGPozuelo de Alarcón, Madrid, 28223, Spain
Contact
-
042
RECRUITINGUsera, Madrid, 28041, Spain
Contact
-
043
RECRUITINGValencia, Valencia, 46010, Spain
Contact
-
044
RECRUITINGOtwock, 05-400, Poland
Contact
-
045
NOT_YET_RECRUITINGPoznan, 60-569, Poland
Contact