New cancer drug YL201 enters human testing for advanced tumors

NCT ID NCT06057922

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental drug, YL201, in about 990 people with advanced solid tumors like lung, prostate, and liver cancers. The goal is to check safety and see if tumors shrink. It is an early-stage trial, so the drug is not yet proven to work.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

YL201 (an experimental drug given by IV infusion every 3 weeks)

What this could lead to

If it works, this could point toward a new treatment option for several advanced cancers that have stopped responding to other therapies.

What could go wrong

This is an early-phase trial (Phase 1/2) with a small number of participants, so the drug may not shrink tumors or may cause significant side effects. Success is far from guaranteed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

biliary tract cancer castration-resistant prostate carcinoma esophageal squamous cell carcinoma head and neck squamous cell carcinoma hepatocellular carcinoma metastatic prostate carcinoma nasopharyngeal carcinoma non-small cell lung carcinoma pancreatic ductal adenocarcinoma sarcoma small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Affiliated Cancer Hospital and Institute of Guangzhou Medical University

    Guangzhou, Guangdong, China

  • Affiliated Cancer Hospital of Guangxi Medical University

    Nanning, Guangxi, China

  • Affiliated Hospital of Chengde Medical University

    Chengde, Hebei, China

  • Affiliated Hospital of Jiangnan University

    Wuxi, Jiangsu, China

  • Anhui Provincial Cancer Hospital

    Hefei, Anhui, China

  • Chongqing University Cancer Hospital

    Chongqing, Chongqing Municipality, China

  • Dongguan People's Hospital

    Dongguan, Guangdong, China

  • First Affiliated Hospital of Gannan Medical University

    Ganzhou, Jiangxi, China

  • Fujian Cancer Hospital

    Fuzhou, Fujian, China

  • Harbin Medical University Cancer Hospital

    Haerbin, Heilongjiang, China

  • Henan Cancer Hospital

    Zhengzhou, Henan, China

  • Hunan Cancer Hospital

    Changsha, Hunan, China

  • Jiangmen Central Hospital

    Jiangmen, Guangdong, China

  • Jiangxi Cancer Hospital (Jiangxi Second People's Hospital)

    Nanchang, Jiangxi, China

  • Jiangyin People's Hospital

    Wuxi, Jiangsu, China

  • Liaoning Cancer Hospital and Institute

    Shenyang, Liaoning, China

  • Linyi Cancer Hospital

    Linyi, Shandong, China

  • Liuzhou People's Hospital

    Liuzhou, Guangxi, China

  • Liuzhou Worker's Hospital

    Liuzhou, Guangxi, China

  • Nantong Tumor Hospital

    Nantong, Jiangsu, China

  • Peking University People's Hospital

    Beijing, Beijing Municipality, China

  • Shandong Cancer Hospital and Institute

    Jinan, Shandong, China

  • Shandong Provincial Hospital

    Jinan, Shandong, China

  • Shanxi Cancer Hospital

    Datong, Shanxi, China

  • Sichuan Cancer Hospital

    Chengdu, Sichuan, China

  • Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University

    Guangzhou, Guangdong, China

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510000, China

  • Taizhou Hospital of Zhejiang Province

    Taizhou, Zhejiang, China

  • The Fifth Affiliated Hospital Sun Yat-Sen University

    Zhuhai, Guangdong, China

  • The First Affiliated Hospital of Anhui Medical University

    Hefei, Anhui, China

  • The First Affiliated Hospital of Hainan Medical University

    Haikou, Hainan, China

  • The First Affiliated Hospital of Henan University of Science and Technology

    Luoyang, Henan, China

  • The First Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, China

  • The First Affiliated Hospital of USTC

    Hefei, Anhui, China

  • The First Affiliated Hospital of Xiamen University

    Xiamen, Fujian, China

  • The First Affiliated Hospital of Xinxiang Medical University

    Xinxiang, Henan, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, China

  • The First Affiliated Hospital, Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China

  • The First Hospital of Jilin University

    Changchun, Jilin, China

  • The First People's Hospital of Changzhou

    Changzhou, Jiangsu, China

  • The Frist People's Hospital of Foshan

    Foshan, Guangdong, China

  • The People's Hospital of Guangxi Zhuang Autonomous Region

    Nanning, Guangxi, China

  • The Second Affiliated Hospital of Guilin Medical University

    Guilin, Guangxi, China

  • The Second Affiliated Hospital of the Chinese People's Liberation Army Air Force Medical University

    Xian, Shanxi, China

  • The Second Hospital of Anhui Medical University

    Hefei, Anhui, China

  • The Second Xiangya Hospital of Central South University

    Changsha, Hunan, China

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, Tianjin Municipality, China

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan, Hubei, China

  • West China Hospital of Sichuan University

    Huaxi, Sichuan, China

  • Xuzhou Central Hospital

    Xuzhou, Jiangsu, China

  • Yuebei People's Hospital

    Shaoguan, Guangdong, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, China