New drug aims to tame lung inflammation and cut steroid dependence

NCT ID NCT05890729

First seen Jan 04, 2026 · Last updated May 14, 2026 · Updated 21 times

Summary

This study tests an experimental drug called XTMAB-16 in people with pulmonary sarcoidosis, a condition causing lung inflammation. The goal is to see if the drug is safe and can help patients reduce or stop using steroids, which have side effects. About 94 adults aged 18-80 with the disease will participate.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • King's College Hospital NHS Foundation Trust

    RECRUITING

    London, England, SE59RS, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NHS Tayside

    RECRUITING

    Perth, Scotland, PH11NX, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Norfolk and Norwich University Hospitals NHS Foundation Trust

    COMPLETED

    Norwich, England, NR47UY, United Kingdom

  • Oxford University Hospitals NHS Foundation Trust

    COMPLETED

    Oxford, England, OX37LE, United Kingdom

  • University College London Hospitals NHS Foundation Trust

    RECRUITING

    London, England, NW12PG, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Hospitals Coventry and Warwickshire NHS Trust

    RECRUITING

    Coventry, England, CV22DX, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Xentria Investigative Site

    RECRUITING

    Birmingham, Alabama, 35233, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Denver, Colorado, 80206, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    COMPLETED

    Jacksonville, Florida, 32209, United States

  • Xentria Investigative Site

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Detroit, Michigan, 48202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    TERMINATED

    Albany, New York, 12208, United States

  • Xentria Investigative Site

    RECRUITING

    New York, New York, 10029, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Greenville, North Carolina, 27858, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Cincinnati, Ohio, 45267, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Philadelphia, Pennsylvania, 19140, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    WITHDRAWN

    Houston, Texas, 77030, United States

  • Xentria Investigative Site

    RECRUITING

    Charlottesville, Virginia, 22903, United States

    Contact Phone: •••-•••-••••

  • Xentria Investigative Site

    RECRUITING

    Prague, 140 59, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Aalborg, 9000, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Aarhus, 8200, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Odense, 5000, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Roskilde, 4000, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Vejle, 7100, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Bielsk Podlaski, 15-044, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Lodz, 90-153, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Barcelona, 08035, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Barcelona, 08036, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xentria Investigative Site

    RECRUITING

    Seville, 41013, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.