New hope for sarcoidosis patients: drug aims to tame lung inflammation and cut steroids
NCT ID NCT05890729
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an experimental drug called XTMAB-16 in adults with pulmonary sarcoidosis, a condition causing lung inflammation. The goal is to see if the drug is safe and can help patients reduce or stop taking steroids, which have serious side effects. About 94 participants will receive multiple doses of the drug over several weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- XTMAB-16 for Pulmonary Sarcoidosis Trial (NCT07680166)
- Efzofitimod for Pulmonary Sarcoidosis Trial NCT05415137
- Acthar Gel for Sarcoidosis: CXCL9 Biomarker Stud NCT02523092
- OATD-01 for Pulmonary Sarcoidosis Trial (NCT06205121)
- FMT for Inflammatory Diseases Trial (NCT04924270)
- Sarcoidosis Medication Adherence Study | NCT05438095
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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King's College Hospital NHS Foundation Trust
COMPLETEDLondon, England, SE59RS, United Kingdom
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NHS Tayside
RECRUITINGPerth, Scotland, PH11NX, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Norfolk and Norwich University Hospitals NHS Foundation Trust
COMPLETEDNorwich, England, NR47UY, United Kingdom
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Oxford University Hospitals NHS Foundation Trust
COMPLETEDOxford, England, OX37LE, United Kingdom
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University College London Hospitals NHS Foundation Trust
RECRUITINGLondon, England, NW12PG, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University Hospitals Coventry and Warwickshire NHS Trust
RECRUITINGCoventry, England, CV22DX, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Xentria Investigative Site
RECRUITINGBirmingham, Alabama, 35233, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGDenver, Colorado, 80206, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
COMPLETEDJacksonville, Florida, 32209, United States
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Xentria Investigative Site
RECRUITINGChicago, Illinois, 60611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGChicago, Illinois, 60612, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGIowa City, Iowa, 52242, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGBaltimore, Maryland, 21287, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGDetroit, Michigan, 48202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGMinneapolis, Minnesota, 55455, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
TERMINATEDAlbany, New York, 12208, United States
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Xentria Investigative Site
RECRUITINGNew York, New York, 10029, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGGreenville, North Carolina, 27858, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGCincinnati, Ohio, 45267, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGCharleston, South Carolina, 29425, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
WITHDRAWNHouston, Texas, 77030, United States
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Xentria Investigative Site
RECRUITINGCharlottesville, Virginia, 22903, United States
Contact Phone: •••-•••-••••
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Xentria Investigative Site
RECRUITINGPrague, 140 59, Czechia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGAalborg, 9000, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGAarhus, 8200, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGOdense, 5000, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGRoskilde, 4000, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGVejle, 7100, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGBielsk Podlaski, 15-044, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGLodz, 90-153, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGBarcelona, 08035, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGBarcelona, 08036, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xentria Investigative Site
RECRUITINGSeville, 41013, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••