New hope for Hard-to-Treat thyroid cancer: drug XL092 enters human trials
NCT ID NCT06959641
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests a drug called XL092 in 33 people with advanced thyroid cancer that has stopped responding to radioiodine therapy. XL092 works by blocking a protein that helps cancer cells grow. The study aims to see if the drug can slow or stop cancer progression.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- XL092 (a tyrosine kinase inhibitor)
- What this could lead to
- If successful, this could provide a new first-line treatment option to control advanced thyroid cancer that no longer responds to radioiodine therapy.
- What could go wrong
- This is a small early-phase trial with only 33 participants, so results may not apply broadly. The drug may cause side effects or fail to slow cancer growth.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Harbor-UCLA Medical Center
RECRUITINGTorrance, California, 90502, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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