New drug trial aims to reduce severe seizures

NCT ID NCT05667142

Recruiting now Disease control Sponsor: Xenon Pharmaceuticals Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding an investigational drug called XEN1101 to a person's current anti-seizure medications can better control severe, full-body convulsive seizures. It will involve about 160 people aged 12 and older who have generalized epilepsy and still experience these seizures despite taking other medications. The main goal is to see if XEN1101 is safe and can reduce the frequency of these seizures compared to a placebo.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PRIMARY GENERALIZED TONIC-CLONIC SEIZURES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ANESC Research
RECRUITING

El Paso, Texas, 79912, United States
Advocate Aurora Research institute, St. Luke's Medical Center
RECRUITING

Milwaukee, Wisconsin, 53215, United States
Atrium Health
RECRUITING

Charlotte, North Carolina, 28203, United States
Austin Health Pharmacy Clinical Trials
RECRUITING

Heidelberg, Victoria, 3084, Australia
Azienda Ospedaliero Universitaria Ospedali Riuniti Ancona
WITHDRAWN

Ancona, 60126, Italy
Azienda Ospedaliero Universitaria Pisana
RECRUITING

Pisa, 56126, Italy
Bethel Epilepsy Centre
RECRUITING

Bielefeld, 33617, Germany
Bluegrass Epilepsy Research, LLC
RECRUITING

Lexington, Kentucky, 40504, United States
Brain Science Research Institute
RECRUITING

Los Angeles, California, 90025, United States
Brigham and Women's Hospital
RECRUITING

Chestnut Hill, Massachusetts, 02467, United States
CHU de Lille, Hôpital Roger Salengro - Neurophysiologie clinique
RECRUITING

Lille, 59037, France
CHU de Rennes - Hôpital Pontchaillou
RECRUITING

Rennes, 35033, France
CHU de Strasbourg - Hôpital de Hautepierre
RECRUITING

Strasbourg, 67098, France
COPERNICUS Podmiot Leczniczy Sp. z o.o.
RECRUITING

Gdansk, 80-803, Poland
Center for Neurologic Research
RECRUITING

Lethbridge, Alberta, T1J 0N9, Canada
Centre Hospitalar Universitario de Lisboa Norte (CHULN)
RECRUITING

Lisbon, 1649-035, Portugal
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
RECRUITING

Lisbon, 1349-019, Portugal
Centro Hospitalar Universitário de Coimbra (CHUC)
RECRUITING

Coimbra, 3000-075, Portugal
Centro Hospitalar Universitário de Santo António
RECRUITING

Porto, 4050-342, Portugal
Centro Hospitalar de Entre o Douro e Vouga
RECRUITING

Santa Maria da Feira, 4520-211, Portugal
Centro de investigación Clinica UC-CICUC
RECRUITING

Santiago, Chile
Centrum Medyczne Neuromed
RECRUITING

Bydgoszcz, 85-163, Poland
Children and Women's Health Centre of BC (BC Children's Hospital)
RECRUITING

Vancouver, British Columbia, V6H 3V4, Canada
Children's Healthcare of Atlanta
RECRUITING

Atlanta, Georgia, 30342, United States
Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195, United States
Clinical Hospital Center Osijek
WITHDRAWN

Osijek, 310 00, Croatia
Clinical Hospital Center Rijeka
WITHDRAWN

Rijeka, 510 00, Croatia
Cliniques Universitaires Saint-Luc
RECRUITING

Brussels, 1200, Belgium
Consultants in Epilepsy and Neurology, PLLC
RECRUITING

Boise, Idaho, 83702, United States
Dent Neurosciences Research Facility
TERMINATED

Amherst, New York, 14226, United States
Duke University Clinical Research
RECRUITING

Durham, North Carolina, 27710, United States
Emory Brain Health Center
RECRUITING

Atlanta, Georgia, 30329, United States
Encore Medical Research of Weston, LLC
RECRUITING

Weston, Florida, 33331, United States
Epilepsiezentrum Kleinwachau gemeinnützige GmbH
WITHDRAWN

Radeberg, 01454, Germany
Epilepsiezentrum im Neuozentrum
RECRUITING

Freiburg im Breisgau, 79106, Germany
Fakultni nemocnice v Motole Neurologicka klinika 2. LF UK a FN Motol
WITHDRAWN

Prague, 150 06, Czechia
First University Multiprofile Hospital for Active Treatment Sofia Sv. Joan Krastitel
WITHDRAWN

Sofia, 1142, Bulgaria
Five Towns Neurology
WITHDRAWN

Woodmere, New York, 11598, United States
Georgia Neurology & Sleep Medicine Associates
WITHDRAWN

Suwanee, Georgia, 30024, United States
Grupo Medico Camino SC
RECRUITING

Mexico City, 03310, Mexico
Hadassah University Medical Center
RECRUITING

Jerusalem, 9112001, Israel
Hawaii Pacific Neuroscience, Comprehensive Epilepsy Center
RECRUITING

Honolulu, Hawaii, 96817, United States
Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon
RECRUITING

Lyon, 9003, France
Hospital Clinico Universitario de Valladolid
WITHDRAWN

Valladolid, 47003, Spain
Hospital Clinico Viña del Mar
RECRUITING

Valparaíso, 2520612, Spain
Hospital General de Agudos J.M. Ramos Mejia
RECRUITING

Buenos Aires, 1221, Argentina
Hospital Italiano
RECRUITING

Buenos Aires, C1181ACH, Argentina
Hospital Regional Universitario de Málaga
WITHDRAWN

Málaga, 29010, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 280 41, Spain
Hospital Universitario Vithas Madrid La Milagrosa
WITHDRAWN

Madrid, 28010, Spain
Hospital da Senhora da Oliveira
RECRUITING

Guimarães, 4835-044, Portugal
Human Science Research Trials S. de R.L. de C.V.
RECRUITING

Mexico City, 14050, Mexico
Hôpital Fondation A. de Rothschild
RECRUITING

Paris, 75019, France
Indiana University School of Medicine
WITHDRAWN

Indianapolis, Indiana, 46202, United States
John Radcliffe Hospital
RECRUITING

Oxford, OX3 9DU, United Kingdom
Kaplan Medical Center
RECRUITING

Rehovot, 7661041, Israel
Kempenhaeghe
RECRUITING

Heeze, 5591BL VE, Netherlands
Klinikum der Universität München
RECRUITING

München, 81377, Germany
Le Centre Hospitalier de l'Universite' de Montreal (CHUM)
RECRUITING

Montreal, Quebec, H2X 0C1, Canada
London Health Sciences Center
RECRUITING

London, Ontario, N6A5A5, Canada
MHATNP 'Sveti Naum' EAD
RECRUITING

Sofia, 1113, Bulgaria
Mater Misericordiae Ltd
RECRUITING

South Brisbane, Queensland, 4101, Australia
Mayo Clinic Florida
RECRUITING

Jacksonville, Florida, 32224, United States
MedStar Franklin Square Medical Center
RECRUITING

Baltimore, Maryland, 21237, United States
Medical University of South Carolina (MUSC)
WITHDRAWN

Charleston, South Carolina, 29425, United States
Medsol Clinical Research Center Harbor Professional Centre
RECRUITING

Port Charlotte, Florida, 33952, United States
Medstar Georgetown University Hospital
RECRUITING

Clinton, Maryland, 20735, United States
Michigan State University Department of Neurology
RECRUITING

East Lansing, Michigan, 48824, United States
Mid Yorkshire Hospitals NHS Trust
RECRUITING

Wakefield, West Yorkshire, WF1 4DG, United Kingdom
Mid-Atlantic Epilepsy and Sleep Center
RECRUITING

Bethesda, Maryland, 20817, United States
Multiprofile hospital for active treatment Puls AD
RECRUITING

Blagoevgrad, 2700, Bulgaria
NZOZ Neuromed M. i M.
WITHDRAWN

Lublin, 20-064, Poland
Neurociencias Estudios Clínicos S.C
RECRUITING

Sinaloa, 80020, Mexico
Northeast Regional Epilepsy Group
RECRUITING

Hackensack, New Jersey, 07601, United States
Novo-Med Zielinski I Wspolnicy Sp. J.
RECRUITING

Katowice, 40-584, Poland
OhioHealth Riverside Methodist Hospital
RECRUITING

Columbus, Ohio, 43214, United States
Onsite Clinical Solutions, LLC
RECRUITING

Charlotte, North Carolina, 28211, United States
Ospedalo Pediatrico Bambino Gesu
RECRUITING

Roma, 00165, Italy
Panhandle Research and Medical Clinic
RECRUITING

Pensacola, Florida, 32503, United States
Philipps-Universität Marburg
RECRUITING

Marburg, 35043, Germany
Policlinico Umberto I
RECRUITING

Roma, 185, Italy
Research Institute of Orlando, LLC
TERMINATED

Orlando, Florida, 32806, United States
STAT Research S.A.
RECRUITING

Buenos Aires, C1023AAB, Argentina
SUNY Upstate Medical University
RECRUITING

Syracuse, New York, 13201, United States
Saint Louis University Medical School
RECRUITING

St Louis, Missouri, 14624, United States
Salford Royal NHS Foundation Trust - Greater Manchester Neuroscience Centre (GMNC)
RECRUITING

Salford, M6 8HD, United Kingdom
Sanatorio del Sur S.A
RECRUITING

San Miguel de Tucumán, 4000, Argentina
Sentara Neurology Specialists
RECRUITING

Virginia Beach, Virginia, 23456, United States
Serenity Research Center, LLC
RECRUITING

Miami, Florida, 33176, United States
Southern Illinois University School of Medicine
RECRUITING

Springfield, Illinois, 62794, United States
Southern Neurology
WITHDRAWN

Kogarah, New South Wales, 2217, Australia
Spectrum Health
RECRUITING

Grand Rapids, Michigan, 49503, United States
St George's University Hospitals NHS Foundation Trust
RECRUITING

London, SW17 0QT, United Kingdom
St Vincent's Hospital Melbourne, Clinical Neurosciences
RECRUITING

Melbourne, Victoria, 3065, Australia
Summa Health Clinical Research Center
RECRUITING

Akron, Ohio, 44304, United States
Temple University Hospital
RECRUITING

Philadelphia, Pennsylvania, 19140, United States
The Alfred Hospital
RECRUITING

Melbourne, VC, 3004, Australia
The Chaim Sheba Medical Center
RECRUITING

Ramat Gan, 6265601, Israel
The Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States
The Royal Melbourne Hospital
RECRUITING

Parkville, 3050, Australia
The Tel Aviv Sourasky Medical Center
RECRUITING

Tel Aviv, 64239, Israel
Twoja Przychodnia Nowosolskie Centrum Medyczne
RECRUITING

Nowa Sól, 67-100, Poland
UMass Memorial Medical Center
RECRUITING

Worcester, Massachusetts, 01655, United States
UPMC Comprehensive Epilepsy Center
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
UTHealth Science Center at Houston
RECRUITING

Houston, Texas, 77030, United States
Unidade Local de Saúde de Matosinhos
RECRUITING

Matosinhos Municipality, 4450-024, Portugal
Universitaetsklinik fuer Kinder
RECRUITING

Linz, 4021, Austria
Universitair Ziekenhuis Gent
RECRUITING

Ghent, 9000, Belgium
University California, Davis Clinical & Translation Science Center Clinical Research (CCRC)
WITHDRAWN

Sacramento, California, 95817, United States
University College London Hospitals NHS Foundation Trust
RECRUITING

London, WC1N 3BG, United Kingdom
University Hospital Center Zagreb
WITHDRAWN

Zagreb, 100 00, Croatia
University Hospital Innsbruck
RECRUITING

Innsbruck, 6020, Austria
University Hospital of Wales
RECRUITING

Cardiff, Wales, CF14 4XW, United Kingdom
University of Alabama - Strada Patient Care Center, Neurology
RECRUITING

Mobile, Alabama, 36604, United States
University of Arizona - Health Science Center
RECRUITING

Tucson, Arizona, 85724, United States
University of Arkansas for Medical Sciences
RECRUITING

Little Rock, Arkansas, 72205, United States
University of California, Irvine - Health Neurology Services
RECRUITING

Orange, California, 92868, United States
University of Colorado Anschutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States
University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States
University of Kentucky Albert B. Chandler Hospital (UK Healthcare)
RECRUITING

Lexington, Kentucky, 40536, United States
University of Maryland Medical Center
RECRUITING

Baltimore, Maryland, 21201, United States
University of Michigan Hospitals
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of South Florida
RECRUITING

Tampa, Florida, 33606, United States
University of Texas Health Science Center at San Antonio
RECRUITING

San Antonio, Texas, 78229, United States
University of Utah Clinical Neurosciences Center
RECRUITING

Salt Lake City, Utah, 84132, United States
University of Washington, Regional Epilepsy Center at Harborview Medical Center
RECRUITING

Seattle, Washington, 98104, United States
Università Degli Studi Gabriele d'Annunzio Di Chieti
RECRUITING

Chieti, 66100, Italy
Universitätsklinik für Neurologie
RECRUITING

Salzburg, 5020, Austria
Universitätsklinik für Neurologie, Medizinische Universität Wien
RECRUITING

Vienna, 1090, Austria
Universitätsklinikum Aachen
RECRUITING

Aachen, D-52074, Germany
Universitätsklinikum Frankfurt
RECRUITING

Frankfurt, 60528, Germany
Universitätsklinikum Tübingen
RECRUITING

Tübingen, 72076, Germany
Universitätsklinikum Ulm
RECRUITING

Ulm, 89081, Germany
Vivantes Humboldt Klinikum
WITHDRAWN

Berlin, 13509, Germany
Wake Forest Baptist Health
RECRUITING

Winston-Salem, North Carolina, 27104, United States
Wayne State University
RECRUITING

Detroit, Michigan, 48201, United States
Xenoscience
RECRUITING

Phoenix, Arizona, 85004, United States

Conditions

Explore the condition pages connected to this study.

PRIMARY GENERALIZED TONIC-CLONIC SEIZURES