New drug trial aims to slash seizure frequency in epilepsy

NCT ID NCT05716100

Recruiting now Disease control Sponsor: Xenon Pharmaceuticals Inc. Source: ClinicalTrials.gov ↗

Summary

This Phase 3 trial is testing whether adding the investigational drug XEN1101 to a person's current seizure medications can safely reduce the number of focal seizures they experience. The study will involve about 360 adults with focal epilepsy who are still having seizures despite taking 1-3 standard medications. Participants will take either XEN1101 or a placebo (a pill with no medicine) daily for 12 weeks while researchers track their seizure frequency and side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

9D University Health Center
RECRUITING

Detroit, Michigan, 48201, United States
Alfred Hospital
RECRUITING

Melbourne, Victoria, 30004, Australia
Austin Epilepsy Care Center
RECRUITING

Austin, Texas, 78758, United States
Austin Health
RECRUITING

Melbourne, Victoria, 3084, Australia
Axis Heilsa S. de R.L. de C.V. Althian
RECRUITING

Monterrey, Mexico
CENyR Centro de Especialidades Neurologicas y Rehabilitacion
RECRUITING

C.a.b.a., C1424, Argentina
CINSAN
WITHDRAWN

Santiago, 8431657, Chile
COPERNICUS Podmiot Leczniczy
RECRUITING

Gdansk, Poland
Centre Hospitalier Universitaire de Lille (CHU de Lille)
RECRUITING

Lille, 59037, France
Centro Hospitalar Lisboa Ocidental
RECRUITING

Lisbon, Portugal
Centro Hospitalar Universitário de Coimbra - CHUC
RECRUITING

Coimbra, Portugal
Centro Hospitalar Universitário de Santo António
RECRUITING

Porto, 4099-001, Portugal
Centro Hospitalar de Entre o Douro e Vouga
RECRUITING

Santa Maria da Feira, 520-211, Portugal
Centro Hospitalar de Lisboa Norte
RECRUITING

Lisbon, 1649-035, Portugal
Centro de Investigacion Clinica UC
RECRUITING

Santiago, 833073, Chile
Chu de Rennes Hôpital Pontchaillou
RECRUITING

Rennes, 35033, France
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Clinica Universidad de Los Andes
WITHDRAWN

Santiago, 7620157, Chile
Clinical Hospital Center Rijeka, Klinika za Neurologiju
WITHDRAWN

Rijeka, 51000, Croatia
Clinical Trials, Inc.
RECRUITING

Little Rock, Arkansas, 72205, United States
Cliniques Universitaires Saint-Luc (UCL)
RECRUITING

Brussels, 1200, Belgium
Consultants in Epilepsy and Neurology, PLLC
RECRUITING

Boise, Idaho, 83702, United States
Duke University Clinic
RECRUITING

Durham, North Carolina, 27705, United States
EUC Hradec Kralove Clinic
WITHDRAWN

Hradec Králové, Czechia
FLENI
RECRUITING

C.a.b.a., C1428DGG, Argentina
Five Towns Neuroscience Research
WITHDRAWN

Woodmere, New York, 11598, United States
Forbeli s.r.o.
RECRUITING

Prague, Czechia
Grupo Medico Camino
RECRUITING

Benito Juárez, Mexico
Hadassah Medical Center
RECRUITING

Jerusalem, 9112001, Israel
Hopital Neurologique Pierre Wertheimer
RECRUITING

Bron, 69500, France
Hospital Britanico de Buenos Aires
RECRUITING

Buenos Aires, C1280AEB, Argentina
Hospital Central Ramon Carrilo
RECRUITING

San Luis, 5701, Argentina
Hospital Clínico San Carlos
RECRUITING

Madrid, 28040, Spain
Hospital Clínico Viña del Mar
RECRUITING

Viña del Mar, Chile
Hospital Córdoba
RECRUITING

Córdoba, X5000, Argentina
Hospital De Alta Complejidad en Red el Cruce
RECRUITING

Buenos Aires, 1888, Argentina
Hospital Italiano
RECRUITING

Buenos Aires, C1199ABB, Argentina
Hospital Pedro Hispano
RECRUITING

Porto, 4464-513, Portugal
Hospital Ramos Mejia
RECRUITING

Buenos Aires, 1221, Argentina
Hospital Universitario Cruces
RECRUITING

Barakaldo, 48903, Spain
Hospital Unversitario Ramon y Cajal
RECRUITING

Madrid, 28034, Spain
Hospital da Senhora da Oliveira
RECRUITING

Guimarães, 4835-044, Portugal
Hospital universitario Fundación Jiménez Díaz
RECRUITING

Madrid, 28040, Spain
Human Science Research Trials
RECRUITING

Mexico City, 14050, Mexico
Hôpital Fondation A. de Rothschild
RECRUITING

Paris, 75019, France
Hôpital de Hautepierre
RECRUITING

Strasbourg, 67098, France
Hôpital de la Pitié Salpêtrière
RECRUITING

Paris, 75013, France
Instituto de Neurologia Cognitiva (INECO)
RECRUITING

Buenos Aires, C1060AAF, Argentina
Kaplan Medical Center
RECRUITING

Rehovot, 76100, Israel
Kempenhaeghe
RECRUITING

Heeze, Netherlands
Krankenhaus Mara gGmbH
RECRUITING

Bielefeld, 33617, Germany
Kuopio University Hospital
RECRUITING

Kuopio, 70210, Finland
MHATNPsy Sveti Naum EAD
RECRUITING

Sofia, 1113, Bulgaria
MTZ Clinical Research Powered by Pratia
RECRUITING

Warsaw, 02-172, Poland
Mayo Clinic Florida
RECRUITING

Jacksonville, Florida, 32224, United States
Medical University of Vienna
RECRUITING

Vienna, 1090, Austria
Medical center OPHTHA-NEURO
RECRUITING

Sofia, 1172, Bulgaria
Mid-Atlantic Epilepsy and Sleep Center
RECRUITING

Bethesda, Maryland, 20817, United States
NZOZ Neuromed M. i M. Nastaj Sp. P.
WITHDRAWN

Lublin, 20-064, Poland
Nemocnicni lekarna FN Motol / Motol University Hospital
RECRUITING

Prague, 150 06, Czechia
Neurocencias Esudios Clinicos S.C.
RECRUITING

Sinaloa, 80020, Mexico
Neurosphera Sp. z o.o.
RECRUITING

Warsaw, 02-829, Poland
Northeast Regional Epilepsy Group
RECRUITING

Hackensack, New Jersey, 07601, United States
OhioHealth
RECRUITING

Columbus, Ohio, 43214, United States
Ospedali Riuniti di Ancona
WITHDRAWN

Ancona, 60126, Italy
Panhandle Research and Medical Clinic
RECRUITING

Gulf Breeze, Florida, 32651, United States
Policlinico Lomas
RECRUITING

Buenos Aires, B1832BQD, Argentina
Poliklinika Bonifarm
RECRUITING

Zagreb, 10000, Croatia
Poliklinika LF MEDICAL
RECRUITING

Zagreb, 1000, Croatia
Prince of Wales Hospital
RECRUITING

Randwick, New South Wales, 2031, Australia
Rancho Research Institute
RECRUITING

Downey, California, 90242, United States
Royal Melbourne Hospital
RECRUITING

Melbourne, 3050, Australia
Royal Prince Alfred Hospital
RECRUITING

Camperdown, New South Wales, 2050, Australia
STAT Resarch S.A.
RECRUITING

Buenos Aires, Argentina
Sanatori del Sur S.A.
RECRUITING

San Miguel de Tucumán, Argentina
Semmelweis Egyetem, Idegsebészeti és Neurointervenciós Klinika
RECRUITING

Budapest, 1145, Hungary
Southern Illinois University School of Medicine
RECRUITING

Springfield, Illinois, 62794, United States
The Chaim Sheba Medical Center
RECRUITING

Ramat Gan, 6265601, Israel
The Tel Aviv Sourasky Medical Center
RECRUITING

Tel Aviv, 64239, Israel
Twoja Przychodnia Nowosolskie Centrum Medyczne
RECRUITING

Nowa Sól, 67-100, Poland
ULS de Trás-os-Montes e Alto Douro
RECRUITING

Vila Real, 5000-508, Portugal
Universitair Ziekenhuis Gent
RECRUITING

Ghent, 9000, Belgium
University Hospital Center Osijek
WITHDRAWN

Osijek, 31000, Croatia
University Hospital Center Zagreb
RECRUITING

Zagreb, 10000, Croatia
University Hospital Frankfurt, ZNN - Epilepsy Center Frankfurt Rhine-Main
RECRUITING

Frankfurt, 60528, Germany
University Hospital Innsbruck
RECRUITING

Innsbruck, Austria
University of California Irvine Health
RECRUITING

Orange, California, 92868, United States
University of California Los Angeles (UCLA)
RECRUITING

Los Angeles, California, 90095, United States
University of Utah Clinical Neurosciences Center
RECRUITING

Salt Lake City, Utah, 84132, United States
Università degli studi di Bari Aldo Moro
RECRUITING

Bari, 70124, Italy
Universitätsklinik für Neurologie
RECRUITING

Salzburg, 5020, Austria
Universitätsklinikum Aachen
RECRUITING

Aachen, D-52074, Germany
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States
Westmead Hospital
RECRUITING

Westmead, New South Wales, 2145, Australia

Conditions

Explore the condition pages connected to this study.

FOCAL ONSET SEIZURES