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New pill xanamem aims to slow Alzheimer's decline

NCT ID NCT06125951

Ongoing Disease control Sponsor: Actinogen Medical Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a daily 10 mg pill called Xanamem can safely slow memory and function loss in people with mild or moderate Alzheimer's dementia. About 247 participants will receive either Xanamem or a placebo for 36 weeks, with an option to continue the drug for up to 108 weeks. The main goal is to see if the drug improves scores on a standard dementia rating scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Xanamem (a drug taken as a daily pill)

What this could lead to

If successful, Xanamem could become a new daily treatment to slow cognitive and functional decline in early Alzheimer's disease.

What could go wrong

This is a mid-stage trial with only 247 participants, so results may not confirm benefit. The drug is still experimental, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE DEMENTIA MODERATE DEMENTIA, MILD

Contacts and locations

Locations

  • ACW Investigative Site 101

    Ivanhoe, Victoria, Australia

  • ACW Investigative Site 102

    Kogarah, New South Wales, Australia

  • ACW Investigative Site 103

    Erina, New South Wales, Australia

  • ACW Investigative Site 104

    Nedlands, Western Australia, Australia

  • ACW Investigative Site 105

    Chermside, Queensland, Australia

  • ACW Investigative Site 106

    Darlinghurst, New South Wales, Australia

  • ACW Investigative Site 107

    Macquarie Park, New South Wales, Australia

  • ACW Investigative Site 108

    Malvern, Victoria, Australia

  • ACW Investigative Site 109

    West Perth, Western Australia, Australia

  • ACW Investigative Site 110

    Woodville South, South Australia, Australia

  • ACW Investigative Site 111

    Newcastle, New South Wales, Australia

  • ACW Investigative Site 112

    Parkville, Victoria, Australia

  • ACW Investigative Site 113

    Birtinya, Queensland, Australia

  • ACW Investigative Site 114

    Bedford Park, South Australia, Australia

  • ACW Investigative Site 115

    Carlton, Victoria, Australia

  • ACW Investigative Site 203

    Delray Beach, Florida, 33445, United States

  • ACW Investigative Site 206

    Toms River, New Jersey, 08755, United States

  • ACW Investigative Site 207

    Decatur, Georgia, 30030, United States

  • ACW Investigative Site 208

    Englewood, Colorado, 80113, United States

  • ACW Investigative Site 209

    Sherman Oaks, California, 91403, United States

  • ACW Investigative Site 210

    Dayton, Ohio, 45459, United States

  • ACW Investigative Site 211

    Denver, Colorado, 80218, United States

  • ACW Investigative Site 212

    Portland, Oregon, 97225, United States

  • ACW Investigative Site 213

    Orange, California, 92866, United States

  • ACW Investigative Site 214

    Albany, New York, 12208, United States

  • ACW Investigative Site 215

    Bellevue, Washington, 98007, United States

  • ACW Investigative Site 216

    East Providence, Rhode Island, 02914, United States

  • ACW Investigative Site 217

    Independence, Ohio, 44131, United States

  • ACW Investigative Site 218

    Carlsbad, California, 92011, United States

  • ACW Investigative Site 219

    Staten Island, New York, 10314, United States

  • ACW Investigative Site 220

    Austin, Texas, 78757, United States

  • ACW Investigative site 201

    Miami, Florida, 33176, United States

  • ACW Investigative site 202

    New Port Richey, Florida, 34652, United States

  • ACW Investigative site 204

    Orlando, Florida, 32803, United States

  • ACW Investigative site 205

    The Villages, Florida, 32162, United States