Pen and paper power: UCLA study tests if writing boosts brain health in seniors
NCT ID NCT05524597
First seen Jun 27, 2026 · Last updated Jul 15, 2026 · Updated 2 times
Summary
This UCLA study is looking for healthy adults aged 65 and older to see if writing about their experiences can affect their brain and body. Over 6 weeks, participants will write once a week and complete online surveys. They will also visit UCLA twice for brain scans, blood tests, and questionnaires. The goal is to understand how expressive writing might influence stress, social connections, and inflammation.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2023
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy adults age 65 years and older Exclusion Criteria: 1. current smokers 2. active, uncontrolled medical disorders 3. chronic infection (e.g., Hepatitis C, HIV) 4. use of certain medications (steroid use, opioid use) 5. psychiatric disorders (e.g., current major depression, bipolar disorder) 6. body mass index (BMI) greater than 35 7. left-handed 8. claustrophobic 9. metal in body Other exclusion criteria may apply.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Center for Cognitive Neuroscience
RECRUITINGLos Angeles, California, 90095, United States
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