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Hidden retainer complication: scientists race to classify wire syndrome

NCT ID NCT07030023

Diagnosis Sponsor: Centre Hospitalier Universitaire de Nice Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 18, 2026 · Last updated Sep 18, 2026

Summary

Wire Syndrome happens when teeth move unexpectedly behind a permanent orthodontic retainer wire, causing new bite problems that are not just normal relapse. Researchers at a French hospital are reviewing dental records and photos from 53 patients to build a severity scale for the condition. They want to create a shared classification that periodontists and orthodontists can use to catch Wire Syndrome earlier and plan better treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If it works, this could give orthodontists and periodontists a shared way to grade Wire Syndrome, which may help them spot it earlier and avoid treatment mistakes.
What could go wrong
This is a small retrospective study of 53 people, so the proposed classification may not fit every patient or may need adjustment before it is widely used.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

53 people

The number who actually took part.

Started

Mar 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of patients who have undergone orthodontic treatment and are currently wearing a fixed orthodontic retainer

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Presence of fixed orthodontic retention (maxillary and/or mandible) * Comprehensive documentation available * Systemically healthy * Presence or not of a Wire Syndrome Exclusion Criteria: * Patient with other orthodontic retention. * Patient unable to understand french

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Orthodontic wires

Contacts and locations

Locations

  • CHU NICE

    Nice, Alpes Maritimes, 06 000, France