Can Full-Body scans catch cancer early in High-Risk patients?

NCT ID NCT02950987

First seen Jan 08, 2026 · Last updated Apr 25, 2026 · Updated 14 times

Summary

This study looks at whether whole body MRI scans can help find cancer early in children and adults with Li-Fraumeni syndrome, a genetic condition that greatly increases cancer risk. About 150 participants will get annual scans for four years to see if they keep coming back and how many cancers are detected. The goal is to improve screening for this high-risk group, not to treat or cure the disease.

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Contacts and locations

Locations

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.