Peptide gel vs. calcium paste: which erases braces white spots best?
NCT ID NCT07146464
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests two treatments for white spot lesions—early signs of decay that often appear after braces. One is a peptide gel that helps rebuild enamel, and the other is a calcium paste that remineralizes teeth. Eighteen people aged 15 to 25 will get both treatments on different sides of their mouth, and researchers will track color and size changes over 9 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Self-Assembling Peptide P11-4 (SAP P11-4) and Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP)
- What this could lead to
- If it works, this could point toward a more effective, non-invasive treatment to improve the appearance of white spots on teeth after braces.
- What could go wrong
- This is a small, early-stage trial with only 18 participants, so results may not apply to everyone. The treatments only address appearance, not deeper decay, and long-term effects are unknown.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Dentistry, Ain Shams University
RECRUITINGCairo, Cairo Governorate, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.