Peptide gel vs. calcium paste: which erases braces white spots best?

NCT ID NCT07146464

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests two treatments for white spot lesions—early signs of decay that often appear after braces. One is a peptide gel that helps rebuild enamel, and the other is a calcium paste that remineralizes teeth. Eighteen people aged 15 to 25 will get both treatments on different sides of their mouth, and researchers will track color and size changes over 9 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Self-Assembling Peptide P11-4 (SAP P11-4) and Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP)

What this could lead to

If it works, this could point toward a more effective, non-invasive treatment to improve the appearance of white spots on teeth after braces.

What could go wrong

This is a small, early-stage trial with only 18 participants, so results may not apply to everyone. The treatments only address appearance, not deeper decay, and long-term effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Faculty of Dentistry, Ain Shams University

    RECRUITING

    Cairo, Cairo Governorate, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••