Can healthy donor cells shrink tumors? new trial aims to find out

NCT ID NCT00900497

ENROLLING_BY_INVITATION Disease control Sponsor: Dipnarine Maharaj Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests whether infusions of white blood cells from healthy, unrelated donors can help treat solid cancers that have not responded to standard treatments. About 29 patients will receive daily infusions over 1-2 weeks, and their tumors will be checked after 3 months. The study focuses on safety, tolerance, and whether the tumors shrink.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: white blood cells (granulocytes) from healthy donors
What this could lead to: If it works, this could point toward a new way to treat solid cancers using donor immune cells.
What could go wrong: This is an early phase 1/2 trial with only 29 participants, so results may not apply widely. There are risks of adverse reactions from the infusions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

graft versus host disease metastatic malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID TUMORS

Contacts and locations

Locations

South Florida Bone Marrow / Stem Cell Transplant Institute

Boynton Beach, Florida, 33437, United States

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