One-Time procedure aims to lock in weight loss after popular drugs

NCT ID NCT06484114

Summary

This study is testing whether a one-time, outpatient endoscopic procedure can help people keep weight off after they stop taking a weight-loss medication (tirzepatide). Participants first take the medication to lose at least 15% of their body weight. They are then randomly assigned to receive either the real procedure or a sham (placebo) procedure to see which group better maintains their weight loss over one year. The goal is to find a lasting solution for weight maintenance after medication ends.

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Contacts and locations

Locations

  • Advent Health

    Orlando, Florida, 32804, United States

  • American Health Network - Franklin

    Franklin, Indiana, 46131, United States

  • American Health Network - Greenfield

    Greenfield, Indiana, 46140, United States

  • American Health Network - Muncie

    Muncie, Indiana, 47304, United States

  • Baylor St. Luke's Medical Center

    Houston, Texas, 77030, United States

  • Cleveland Clinic, Weston

    Weston, Florida, 33331, United States

  • Dartmouth-Hitchcock Medical Center

    Lebanon, New Hampshire, 03756, United States

  • Encore Borland-Groover Clinical Research

    Jacksonville, Florida, 32256, United States

  • Helios Clinical Research

    Phoenix, Arizona, 85028, United States

  • Hoag Hospital

    Newport Beach, California, 92663, United States

  • Honor Health

    Scottsdale, Arizona, 85258, United States

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • International Research Associates

    Miami, Florida, 33183, United States

  • Investigators Research Group, LLC

    Brownsburg, Indiana, 46112, United States

  • Jacksonville Center for Clinical Research

    Jacksonville, Florida, 32216, United States

  • Juno Research, LLC

    Houston, Texas, 77040, United States

  • K2 Medical Research South Orlando

    Orlando, Florida, 32806, United States

  • Metabolic Research Institute

    West Palm Beach, Florida, 33401, United States

  • NYC Research, Inc. (Endocrine Associates of West Village)

    Long Island City, New York, 11106, United States

  • NYU-Langone

    New York, New York, 10016, United States

  • Nature Coast Clinical Research

    Inverness, Florida, 32162, United States

  • Orlando Health Weight Loss and Bariatric Surgery Institute

    Orlando, Florida, 32806, United States

  • Preferred Primary Care Physician

    Pittsburgh, Pennsylvania, 15326, United States

  • Preferred Primary Care Physician

    Uniontown, Pennsylvania, 15401, United States

  • Preferred Primary Care Physician Pittsburgh

    Pittsburgh, Pennsylvania, 15243, United States

  • Simcare Medical Research LLC

    Sugar Land, Texas, 77478, United States

  • Synexus Clinical Research Institute - The Villages (AES)

    The Villages, Florida, 32162, United States

  • UCLA Santa Monica Medical Center

    Santa Monica, California, 90095, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Washington, Seattle

    Seattle, Washington, 98109, United States

  • West Virginia University

    Morgantown, West Virginia, 26506, United States

  • Zenith Clinical Research

    Hollywood, Florida, 33021, United States

Conditions

Explore the condition pages connected to this study.