Major trial tests new weekly shot for significant, Long-Term weight loss

NCT ID NCT06066515

Summary

This study tested whether a weekly injectable medication called survodutide helps adults with overweight or obesity lose weight. Over 700 participants, who had previously struggled to lose weight through diet alone, received either the drug or a placebo for about a year and a half, alongside diet and exercise counseling. The main goal was to see how much body weight changed and how many people achieved significant weight loss.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AMR Lexington

    Lexington, Kentucky, 40509, United States

  • ASZ - Campus Aalst

    Aalst, 9300, Belgium

  • Accellacare-Wilmington-67123

    Wilmington, North Carolina, 28401, United States

  • Affiliated Hospital of Jiangsu University

    Zhenjiang, 212013, China

  • Aggarwal and Associates Ltd.

    Brampton, Ontario, L6T 0G1, Canada

  • Ajou University Hospital

    Suwon, 16499, South Korea

  • Albion Finch Medical Centre

    Toronto, Ontario, M9V 4B4, Canada

  • Alliance for Multispecialty Research, LLC - Doral

    Doral, Florida, 33172, United States

  • Austin Health

    Heidelberg, Victoria, 3084, Australia

  • Baker Heart and Diabetes Institute

    Melbourne, Victoria, 3004, Australia

  • Beijing Pinggu Hospital

    Beijing, 101200, China

  • Bradford on Avon Health Centre

    Bradford-on-Avon, BA15 1DQ, United Kingdom

  • Burbage Surgery

    Burbage, Hinkley, LE10 2SE, United Kingdom

  • CORE Research Group

    Milton, Queensland, 4064, Australia

  • CRST - Clinical Research Services Turku

    Turku, 20520, Finland

  • Center Hospital of Jinan

    Jinan, 250013, China

  • Changzhou Second People's Hospital

    Changzhou, 213004, China

  • Clifton Medical Centre, Rotherham

    Rotherham, S65 1DA, United Kingdom

  • Clinical Research Center METABOLICA lek. Robert Witek

    Tarnów, 33-100, Poland

  • Consano Clinical Research

    Shavano Park, Texas, 78231, United States

  • Diabetes & Glandular Disease Clinic, P.A.

    San Antonio, Texas, 78229, United States

  • Diabetes Zentrum Hamburg West

    Hamburg, 22607, Germany

  • Diablo Clinical Research

    Walnut Creek, California, 94598, United States

  • Dongguk University Ilsan Hospital

    Goyang, 10326, South Korea

  • Dr. James Lai

    Vancouver, British Columbia, V5Z 4E1, Canada

  • ETG Lublin

    Lublin, 20-412, Poland

  • ETG Siedlce

    Siedlce, 08-110, Poland

  • East Coast Institute for Research, LLC - Jacksonville

    Jacksonville, Florida, 32216, United States

  • East-West Medical Research

    Honolulu, Hawaii, 96814, United States

  • Edegem - UNIV UZ Antwerpen

    Edegem, 2650, Belgium

  • EmVenio Research-Oklahoma City-70053

    Oklahoma City, Oklahoma, 73139, United States

  • EmVenio Research-Phoenix-69743

    Phoenix, Arizona, 85032, United States

  • Encompass Clinical Research, Spring Valley

    Spring Valley, California, 91978, United States

  • Evanston Premier Healthcare Research LLC

    Skokie, Illinois, 60077, United States

  • Forskningsenheten Carlanderska

    Gothenburg, 40545, Sweden

  • Forth Clinical Hospital of Harbin Medical University

    Harbin, 150599, China

  • Franciscus Gasthuis

    Rotterdam, 3045 PM, Netherlands

  • Fukuhama Chuo Clinic

    Fukuoka, Fukuoka, 810-0066, Japan

  • Gachon University Gil Medical Center

    Incheon, 21565, South Korea

  • Griffith Health

    Southport, Queensland, 4125, Australia

  • Guangdong Provincial People's Hospital

    Guangzhou, 510080, China

  • HUS, Lihavuustutkimusyksikkö Biomedicum Helsinki

    Helsinki, 00290, Finland

  • Hachioji Diabetes Clinic

    Tokyo, Hachioji, 192-0083, Japan

  • Hunter Diabetes Centre

    Merewether, New South Wales, 2291, Australia

  • Huzhou Central Hospital

    Huzhou, 313000, China

  • InnoDiab Forschung GmbH

    Essen, 45136, Germany

  • Institut für Diabetesforschung Münster GmbH

    Münster, 48145, Germany

  • Itä-Suomen yliopisto/Health Step Finland Oy

    Kuopio, 70600, Finland

  • James Cha, MD

    Oshawa, Ontario, L1J 2K1, Canada

  • Juno Research, LLC

    Houston, Texas, 77040, United States

  • Kangbuk Samsung Hospital

    Seoul, 110-746, South Korea

  • Keogh Institute for Medical Research

    Nedlands, Western Australia, 6009, Australia

  • Kiltearn Medical Centre

    Nantwich, CW5 5NX, United Kingdom

  • Kobe University Hospital

    Hyogo, Kobe, 650-0017, Japan

  • Kyungpook National University Hospital

    Daegu, 41944, South Korea

  • L-MARC Research Center

    Louisville, Kentucky, 40213, United States

  • Ladulaas Kliniska Studier

    Borås, 506 30, Sweden

  • Lucas Research, Inc.

    Morehead City, North Carolina, 28557, United States

  • MVZ im Altstadt-Caree Fulda GmbH

    Fulda, 36037, Germany

  • Manassas Clinical Research Center

    Manassas, Virginia, 20110, United States

  • Medicinmottagning 5/Överviktsenheten

    Örebro, 70362, Sweden

  • Milestone Research Inc.

    London, Ontario, N5W 6A2, Canada

  • Monash University

    Box Hill, Victoria, 3128, Australia

  • New Horizon Research Center-Miami-69732

    Miami, Florida, 33165, United States

  • Noritake Clinic

    Ibaraki, Ushiku, 300-1207, Japan

  • Optimal Clinical Trials North

    Rosedale, Auckland, 0632, New Zealand

  • P3 Research Dunedin

    Dunedin, 9016, New Zealand

  • P3 Research-Newtown Wellington NZ-33770

    Newtown Wellington NZ, 6021, New Zealand

  • P3 Research-Tauranga-34833

    Tauranga, 3110, New Zealand

  • PI HOUSE Sp. z o.o., Gdansk

    Gdansk, 80-546, Poland

  • PT & R

    Born, 6121 XK, Netherlands

  • Peking University People's Hospital

    Beijing, 100044, China

  • Physicians East, PA

    Greenville, North Carolina, 27834, United States

  • Pingxiang People's Hospital

    Pingxiang, 337000, China

  • Power Clinical Research

    Montreal, Quebec, H3M 1L3, Canada

  • Premier Research, Inc.

    Trenton, New Jersey, 08611, United States

  • Rainier Clinical Research Center

    Renton, Washington, 98057, United States

  • Roeselare - HOSP AZ Delta

    Roeselare, 8800, Belgium

  • Sabbatsbergs sjukhus

    Stockholm, 113 61, Sweden

  • Sameh Fikry Medicine Professional Corporation

    Waterloo, Ontario, N2J 1C4, Canada

  • Seoul National University Bundang Hospital

    Seongnam, 13620, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital

    Seoul, 03722, South Korea

  • Shanghai Fifth People's Hospital affiliated to Fudan University

    Shanghai, 200240, China

  • Shanghai Municipal Hospital of Traditional Chinese Medicine

    Shanghai, 200071, China

  • Siping Central People's Hospital

    Siping, 136000, China

  • Soka Sugiura Naika Clinic

    Saitama, Soka, 340-0034, Japan

  • Solaris Clinical Research

    Meridian, Idaho, 83646, United States

  • Southern Clinical Trials Tasman

    Nelson, 7011, New Zealand

  • Southgate Medical Group/ Southgate Medical Park

    West Seneca, New York, 14224, United States

  • Stouffville Medical Research Institute Inc.

    Stouffville, Ontario, L4A 1H2, Canada

  • StudyCor Oy

    Jyväskylä, 40620, Finland

  • StudyMetrix Research, LLC

    City of Saint Peters, Missouri, 63303, United States

  • Suzhou Municipal Hospital

    Suzhou, 215002, China

  • Texas Diabetes and Endocrinology

    Austin, Texas, 78731, United States

  • The Catholic University of Korea, Bucheon St.Mary's Hospital

    Bucheon-si, 14647, South Korea

  • The Catholic University of Korea, Yeouido St.Mary's Hospital

    Seoul, 07345, South Korea

  • The First Affiliated Hospital of Henan University of Science and Technology

    Luoyang, 471000, China

  • The First Affiliated Hospital of Xi'an Medical University

    Xi'an, 710077, China

  • The First Hospital of Jilin University

    Changchun, 130021, China

  • The Second Affiliated Hospital of Nanjing Medical University

    Nanjing, 210011, China

  • The Second Affiliated Hospital of Zhengzhou University

    Zhengzhou, 100029, China

  • The Wharton Medical Clinic Clinical Trials Inc.

    Hamilton, Ontario, L8L 5G8, Canada

  • Tianjin Medical University General Hospital

    Tianjin, 30052, China

  • Trial Management Associates

    Myrtle Beach, South Carolina, 29572, United States

  • Trowbridge Health Centre

    Trowbridge, BA14 8LW, United Kingdom

  • UZ Leuven

    Leuven, 3000, Belgium

  • Universitair Medisch Centrum Groningen

    Groningen, 9713 EZ, Netherlands

  • University of Florida

    Gainesville, Florida, 32610, United States

  • Valley Weight Loss Clinic

    Fargo, North Dakota, 58104, United States

  • Velocity Clinical Research - Binghamton

    Binghamton, New York, 13905, United States

  • Velocity Clinical Research-Sioux City-69728

    Sioux City, Iowa, 51106, United States

  • Velocity Clinical Research-Valparaiso-68883

    Valparaiso, Indiana, 46383, United States

  • Velocity Nova Sp z o.o.

    Puławy, 24-100, Poland

  • ViaCar Recherches Cliniques Inc. (Greenfield Park)

    Greenfield Park, Quebec, J4V 2G8, Canada

  • Waterloo Medical Centre

    Blackpool, FY4 3AD, United Kingdom

  • West Orange Endocrinology

    Ocoee, Florida, 34761, United States

  • Yale University School of Medicine

    New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.