Scientists hunt for clues to lung cancer drug resistance

NCT ID NCT03969823

First seen Apr 25, 2026 · Last updated May 12, 2026 · Updated 2 times

Summary

This study looks at why advanced lung cancer with a specific gene change (EGFR mutation) stops responding to the targeted drug osimertinib. About 148 adults will take osimertinib daily, and researchers will analyze tumor samples when the cancer progresses. The goal is to find new ways to overcome drug resistance and improve treatment.

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Contacts and locations

Locations

  • Borame Medical Center

    Seoul, South Korea

  • Seoul National University Bundang Hospital

    Seongnam, South Korea

  • Seoul National University Hospital

    Seoul, South Korea

Conditions

Explore the condition pages connected to this study.