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Treadmill walking with leg cuffs boosts lung power in older women

NCT ID NCT07694349

Disease control Sponsor: Universidad Santo Tomas, Chile Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This pilot study tested whether 12 months of moderate treadmill walking with blood flow restriction (BFR) could improve lung function in healthy older women aged 60-80. Participants walked three times a week, with some wearing pneumatic cuffs on their thighs to partially restrict blood flow. The BFR group showed significant improvements in key lung measurements and a lower resting heart rate, with no side effects reported. The findings suggest that adding BFR to walking may be a safe way to enhance respiratory health in older adults.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Blood flow restriction via pneumatic cuffs
What this could lead to
If confirmed, this approach could offer a simple exercise strategy to improve lung function and heart health in older adults.
What could go wrong
This is a small pilot study with only 14 participants, so results may not apply to everyone. Longer and larger trials are needed to confirm safety and effectiveness.

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

14 people

The number who actually took part.

Started

Jan 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 80 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged 60 to 80 years without a diagnosis of chronic non-communicable diseases. * Physically active individuals. * At least 3 consecutive months of participation in structured exercise programs. * Weekly physical activity volume ≥ 180 minutes, assessed using the Global Physical Activity Questionnaire (GPAQ). Exclusion Criteria: * Use of ergogenic aids. * Current smoking habit. * Diagnosis of cardiometabolic diseases. * Presence of neurological disorders or musculoskeletal impairments affecting the lower extremities. * Peripheral vascular diseases.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Older women

Contacts and locations

Locations

  • Clinica Oces

    Santiago, 8320000, Chile

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