New drug may supercharge walking recovery after spinal cord injury

NCT ID NCT05217498

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 24 times

Summary

This study tests whether a drug called istradefylline can make walking therapy more effective for people with chronic, incomplete spinal cord injury. The therapy uses brief low-oxygen breathing to spark nerve growth, but a natural chemical called adenosine may limit its benefits. The drug blocks adenosine to help the nervous system strengthen walking pathways. About 40 adults aged 18-75 with long-term spinal cord injury will take part.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Spaulding Rehabilitation Hospital

    Cambridge, Massachusetts, 02138, United States

Conditions

Explore the condition pages connected to this study.