Stem cells may free some with type 1 diabetes from insulin shots
NCT ID NCT04786262
First seen Mar 26, 2026 · Last updated May 13, 2026 · Updated 9 times
Summary
This study tests a treatment called VX-880 for people with type 1 diabetes who have severe low blood sugar episodes. The therapy uses special cells that can make insulin, aiming to reduce or eliminate the need for insulin injections. About 52 adults will receive the treatment and be monitored for safety and how well it controls blood sugar.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Baylor Scott and White Research Institute
RECRUITINGDallas, Texas, 75246, United States
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CHU Lille
RECRUITINGLille, France
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Cardiovascular, Metabolic Medicine and Sciences, King's College London
RECRUITINGLondon, United Kingdom
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Centre de recherche en Biomédecine de Strasbourg
RECRUITINGStrasbourg, France
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Churchill Hospital
RECRUITINGHeadington, Oxford, United Kingdom
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City of Hope
RECRUITINGDuarte, California, 91010, United States
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Dresden Center for Islet Transplantation
RECRUITINGDresden, Germany
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Hopiteaux Universitaires de Geneve
RECRUITINGGeneva, Switzerland
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Hospital of the University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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IRCCS Ospedale San Raffaele
RECRUITINGMilan, Italy
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
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King Abdullah International Medical Research Center (KAIMRC) - Riyadh - Endocrinology
RECRUITINGRiyadh, Saudi Arabia
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King Faisal Specialist Hospital & Research Centre - Riyadh - Endocrinology
RECRUITINGRiyadh, Saudi Arabia
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Leiden University
RECRUITINGLeiden, Netherlands
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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McGill University Health Centre
RECRUITINGMontreal, Canada
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Northwestern Organ Transplant Center
COMPLETEDChicago, Illinois, 60611, United States
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Oslo University Hospital
RECRUITINGOslo, Norway
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Royal Infirmary of Edinburgh
RECRUITINGEdinburgh, United Kingdom
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The Newcastle upon Tyne Hospitals NHS Foundation Trust
RECRUITINGNewcastle upon Tyne, United Kingdom
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Toronto General Hospital (TGH)
RECRUITINGToronto, Canada
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UHealth Diabetes Research Institute
RECRUITINGMiami, Florida, 33136, United States
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University of Alberta, Edmonton
RECRUITINGEdmonton, Canada
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University of California San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
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University of Pittsburgh Medical Center Montefiore
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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University of Wisconsin
RECRUITINGMadison, Wisconsin, 53792, United States
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VCU Medical Center, Richmond
RECRUITINGRichmond, Virginia, 23298, United States
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Vancouver General Hospital
RECRUITINGVancouver, Canada
Conditions
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