New pill aims to tame ulcerative colitis Flare-Ups

NCT ID NCT05156125

Terminated Disease control Sponsor: Oppilan Pharma Ltd Source: ClinicalTrials.gov ↗

First seen May 02, 2026 · Last updated May 14, 2026 · Updated 2 times

Summary

This study tested whether a daily tablet called VTX002 can safely help people with moderate to severe ulcerative colitis (UC) feel better and reduce gut inflammation. About 213 adults with UC took either a low dose, a high dose, or a placebo pill for 13 weeks, with some continuing treatment for up to 36 months. The main goal was to see if more people on VTX002 reached remission (fewer bathroom trips, no blood in stool, and a healthier colon lining) compared to placebo. The study was stopped early, so results are limited.

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Contacts and locations

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Locations

Local Site # 100002

Rousse, Bulgaria
Local Site # 100005

Rousse, Bulgaria
Local Site # 203001

Slaný, Czechia
Local Site # 203002

Hradec Králové, Czechia
Local Site # 203004

Ústí nad Labem, Czechia
Local Site # 250001

Nantes, France
Local Site # 250003

Vandœuvre-lès-Nancy, France
Local Site # 250004

Caen, France
Local Site # 268001

Tbilisi, Georgia
Local Site # 268002

Tbilisi, Georgia
Local Site # 268003

Tbilisi, Georgia
Local Site # 268004

Tbilisi, Georgia
Local Site # 268005

Tbilisi, Georgia
Local Site # 268006

Tbilisi, Georgia
Local Site # 276003

Nordhausen, Germany
Local Site # 276005

Berlin, Germany
Local Site # 276007

Duisburg, Germany
Local Site # 276008

Brandenburg an der Havel, Germany
Local Site # 276009

Halle, Germany
Local Site # 348001

Budapest, Hungary
Local Site # 348002

Székesfehérvár, Hungary
Local Site # 348003

Budapest, Hungary
Local Site # 348004

Békéscsaba, Hungary
Local Site # 356001

Ahmedabad, India
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Jaipur, India
Local Site # 356005

Sūrat, India
Local Site # 380001

Negrar, Italy
Local Site # 380002

San Giovanni Rotondo, Italy
Local Site # 380004

Pavia, Italy
Local Site # 380008

Rome, Italy
Local Site # 380009

Milan, Italy
Local Site # 410002

Seoul, South Korea
Local Site # 410003

Daegu, South Korea
Local Site # 410004

Wŏnju, South Korea
Local Site # 440001

Vilnius, Lithuania
Local Site # 440002

Panevezys, Lithuania
Local Site # 616001

Lodz, Poland
Local Site # 616002

Wroclaw, Poland
Local Site # 616003

Warsaw, Poland
Local Site # 616004

Oświęcim, Poland
Local Site # 616006

Warsaw, Poland
Local Site # 616007

Sosnowiec, Poland
Local Site # 616008

Poznan, Poland
Local Site # 616009

Wroclaw, Poland
Local Site # 616010

Bydgoszcz, Poland
Local Site # 616011

Piotrkow Trybunalski, Poland
Local Site # 616012

Jelenia Góra, Poland
Local Site # 616013

Wroclaw, Poland
Local Site # 616014

Rzeszów, Poland
Local Site # 616015

Lublin, Poland
Local Site # 616017

Lodz, Poland
Local Site # 688001

Zrenjanin, Serbia
Local Site # 688002

Belgrade, Serbia
Local Site # 688003

Belgrade, Serbia
Local Site # 688004

Belgrade, Serbia
Local Site # 703001

Košice, Slovakia
Local Site # 703002

Šahy, Slovakia
Local Site # 703003

Prešov, Slovakia
Local Site # 840001

Ventura, California, 93003, United States
Local Site # 8400039

Lubbock, Texas, 79424, United States
Local Site # 840006

Miami, Florida, 33165, United States
Local Site # 840007

San Marcos, Texas, 78666, United States
Local Site # 840010

Oklahoma City, Oklahoma, 73101, United States
Local Site # 840013

Garland, Texas, 75044, United States
Local Site # 840016

Southlake, Texas, 76092, United States
Local Site # 840018

Atlanta, Georgia, 30342, United States
Local Site # 840026

Lancaster, California, 93534, United States
Local Site # 840028

Tyler, Texas, 75701, United States
Local Site # 840030

Garden Grove, California, 92845, United States
Local Site # 840033

McAllen, Texas, 78503, United States
Local Site # 840040

San Diego, California, 92123, United States
Local Site # 840042

Shreveport, Louisiana, 71105, United States
Local Site # 840043

Dayton, Ohio, 45415, United States
Local Site # 840044

Ypsilanti, Michigan, 48197, United States
Local Site # 840045

Myrtle Beach, South Carolina, 29572, United States
Local Site # 840046

New Albany, Indiana, 47150, United States
Local Site # 840049

Kissimmee, Florida, 34744, United States

Conditions

Explore the condition pages connected to this study.

COLITIS ULCERATIVE