New hope for Hard-to-Treat cancers: experimental drug VT3989 enters human trials

NCT ID NCT04665206

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 27 times

Summary

This study is testing an experimental drug called VT3989, taken as a pill once a day, for people with advanced solid tumors or mesothelioma that have stopped responding to standard treatments. The goal is to find safe doses and see if the drug can shrink tumors or slow cancer growth. About 434 adults will participate, and the drug may be given alone or combined with other therapies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Linear Clinical Research

    RECRUITING

    Nedlands, Western Australia, 6009, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • M Health Fairview University of Minnesota Medical Center

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Monash Health

    RECRUITING

    Clayton, Victoria, 3168, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT Oncology

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peter MacCullum Cancer Centre

    RECRUITING

    Melbourne, Victoria, 3000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCSF Helen Diller Family Comprehensive Cancer Center

    RECRUITING

    San Francisco, California, 94158, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Chicago Medical Center

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Virginia Cancer Specialists, PC

    RECRUITING

    Arlington, Virginia, 22201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.