Heart rhythm showdown: second ablation or drugs after first success?

NCT ID NCT06669299

Recruiting now Disease control Sponsor: IRCCS Ospedale San Raffaele Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at people with an implanted defibrillator who had a successful first procedure to fix a dangerous fast heart rhythm (ventricular tachycardia). A few days later, they get a non-invasive heart stimulation test. If the test triggers the rhythm again, patients are randomly assigned to either a second ablation or medication. The goal is to see which approach better prevents the rhythm from coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: catheter ablation procedure
What this could lead to: If successful, this could establish a better strategy to prevent life-threatening heart rhythm recurrences after a first ablation, reducing the need for medication.
What could go wrong: This is a small, early-phase study with only 51 participants, so results may not apply broadly. The procedure carries risks like bleeding, infection, or heart damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VENTRICULAR TACHYCARDIA (VT)

Contacts and locations

Locations

San Raffaele Hospital, Arrhythmology and Electrophysiology unit
RECRUITING

Milan, Italy, 20132, Italy

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