Sleeve gastrectomy vs. lifestyle: which tames fatty liver disease?
NCT ID NCT03587831
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two approaches for treating non-alcoholic steatohepatitis (NASH), a serious liver condition linked to obesity. Half of the 48 participants will receive vertical sleeve gastrectomy surgery along with lifestyle counseling, while the other half will get lifestyle counseling alone. Researchers will measure liver health after 12 months to see which group improves more.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vertical sleeve gastrectomy surgery and lifestyle modification counseling
What this could lead to
If successful, this could show that adding weight-loss surgery to lifestyle changes is a safe and effective way to reduce liver damage in NASH patients.
What could go wrong
This is a small pilot study with only 48 people, so results may not apply to everyone. Surgery also carries risks like infection or complications.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Minneapolis VA Medical Center
RECRUITINGMinneapolis, Minnesota, 55417, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Pennington Biomedical Research Center
RECRUITINGBaton Rouge, Louisiana, 70808, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of San Fransisco
RECRUITINGSan Francisco, California, 94143, United States
Contact
Contact Email: •••••@•••••
Contact Email: •••••@•••••
Contact