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Experimental treatment tested for critical liver failure

NCT ID NCT05900050

Terminated Disease control Sponsor: Genfit Source: ClinicalTrials.gov ↗

Summary

This study tested if adding an experimental drug called VS-01 to standard care could help adults with a sudden, severe worsening of chronic liver failure (ACLF) and fluid buildup in the abdomen. The trial was small, ended early, and compared VS-01 plus standard care to standard care alone. The main goal was to see if the treatment improved a score that measures the severity of liver failure after one week.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ASST Grande Ospedale Metropolitano Niguarda

    Milan, 20162, Italy

  • Azienda Ospedaliero-Universitaria Policlinico Umberto I

    Roma, 00185, Italy

  • Baylor Clinic

    Houston, Texas, 77030, United States

  • CHU Rennes - Hôpital Pontchaillou

    Rennes, 35033, France

  • Centre Hospitalier Régional Universitaire de Tours

    Chambray-lès-Tours, 37170, France

  • Charité Universitätsmedizin Berlin

    Berlin, State of Berlin, 13353, Germany

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Columbia University Medical Center/ New York Presbyterian Hospital

    New York, New York, 10032, United States

  • Debreceni Egyetem Klinikai Központ

    Debrecen, 4032, Hungary

  • Heves Vármegyei Markhot Ferenc Oktatókórház és Rendelőintézet

    Eger, 3300, Hungary

  • Hospital Clínic de Barcelona

    Barcelona, Barcelona, 08036, Spain

  • Hôpital Universitaire Pitié Salpêtrière

    Paris, 75013, France

  • Hôpital de la Croix Rousse

    Lyon, 69004, France

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Medizinische Hochschule Hannover

    Hanover, 30625, Germany

  • Medstar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Piedmont Atlanta Hospital

    Atlanta, Georgia, 30309, United States

  • Richmond VA Medical Center

    Richmond, Virginia, 23249, United States

  • Tampa General Hospital

    Tampa, Florida, 33606, United States

  • The Liver Institute at Methodist Dallas

    Dallas, Texas, 75203, United States

  • Universitair Ziekenhuis Antwerpen

    Edegem, 2650, Belgium

  • Universitatsklinikum Munster

    Münster, North Rhine-Westphalia, 48149, Germany

  • University of California Davis Medical Center

    Sacramento, California, 95817, United States

  • University of Missouri Health Care

    Columbia, Missouri, 65212, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.

ACUTE ON CHRONIC LIVER FAILURE ASCITES