Can VR and brain zaps lift Post-Stroke depression?
NCT ID NCT07422740
First seen Feb 21, 2026 · Last updated Jun 22, 2026 · Updated 19 times
Summary
This study tests whether combining virtual reality mindfulness therapy (VR-MBCT) with a gentle brain stimulation technique (tDCS) can help treat depression that occurs after a stroke. The trial will enroll 120 adults aged 18-65 who have had a stroke and have moderate to severe depression. Participants will be randomly assigned to receive either the active treatments, a placebo version, or standard care, and their depression symptoms will be tracked over 28 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
virtual reality mindfulness-based cognitive therapy and transcranial direct current stimulation
What this could lead to
If it works, this could offer a new, non-drug way to reduce depression symptoms in people who have had a stroke.
What could go wrong
This is an early-stage trial with only 120 participants, so results may not apply to everyone. The treatments are still experimental and may not be more effective than standard care.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.