New pill aims to calm social anxiety on the spot

NCT ID NCT07221578

Ongoing Symptom relief Sponsor: Vanda Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times

Summary

This phase 3 trial tests a single oral dose of VQW-765 versus placebo for quickly reducing acute anxiety in adults with social anxiety disorder. About 500 participants will take the drug as needed before anxiety-provoking situations. The study measures distress levels during and before the event.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: VQW-765 (oral capsule)
What this could lead to: If it works, this could provide a fast-acting, on-demand option to ease acute anxiety during social situations for people with social anxiety disorder.
What could go wrong: This is a late-stage trial, but the drug is still experimental. It may not work better than placebo, and side effects are possible. Success depends on real-world effectiveness and safety.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

social phobia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOCIAL ANXIETY DISORDER (SAD)

Contacts and locations

Locations

Vanda Investigational Site

Phoenix, Arizona, 85012, United States
Vanda Investigational Site

Scottsdale, Arizona, 85260, United States
Vanda Investigational Site

Encino, California, 91316, United States
Vanda Investigational Site

Mission Viejo, California, 92691, United States
Vanda Investigational Site

San Diego, California, 92123, United States
Vanda Investigational Site

San Jose, California, 95124, United States
Vanda Investigational Site

Walnut Creek, California, 94596, United States
Vanda Investigational Site

Denver, Colorado, 80209, United States
Vanda Investigational Site

Jacksonville, Florida, 32256, United States
Vanda Investigational Site

Miami, Florida, 33125, United States
Vanda Investigational Site

Orlando, Florida, 32801, United States
Vanda Investigational Site

Tampa, Florida, 33629, United States
Vanda Investigational Site

Atlanta, Georgia, 30329, United States
Vanda Investigational Site

Suwanee, Georgia, 30024, United States
Vanda Investigational Site

New Orleans, Louisiana, 70115, United States
Vanda Investigational Site

Pikesville, Maryland, 21208, United States
Vanda Investigational Site

Rockville, Maryland, 20852, United States
Vanda Investigational Site

Towson, Maryland, 21204, United States
Vanda Investigational Site

Saint Charles, Missouri, 63304, United States
Vanda Investigational Site

St Louis, Missouri, 63182, United States
Vanda Investigational Site

Las Vegas, Nevada, 89102, United States
Vanda Investigational Site

Princeton, New Jersey, 08540, United States
Vanda Investigational Site

Albuquerque, New Mexico, 87109, United States
Vanda Investigational Site

New York, New York, 10016, United States
Vanda Investigational Site

New York, New York, 10036, United States
Vanda Investigational Site

Charlotte, North Carolina, 28210, United States
Vanda Investigational Site

Wilmington, North Carolina, 28403, United States
Vanda Investigational Site

Houston, Texas, 77081, United States
Vanda Investigational Site

Wichita Falls, Texas, 76309, United States
Vanda Investigational Site

Orem, Utah, 84097, United States

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