Smart pain pump could stop Opioid-Induced breathing trouble

NCT ID NCT02804022

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial tests a new pain relief system for women after surgery. The system delivers morphine through an IV, but it uses a smart algorithm that watches oxygen levels, breathing, and heart rate in real time. If these vital signs show a problem, the pump can adjust the pain medication to help prevent respiratory depression. The study will see if this approach reduces dangerous drops in breathing or heart rate while still controlling pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
A device that delivers morphine through an IV, with an algorithm that adjusts dosing based on continuous monitoring of oxygen, breathing, and heart rate.
What this could lead to
If successful, this could lead to a safer way to manage post-surgical pain, reducing the risk of respiratory depression in patients receiving opioids.
What could go wrong
This is a small early-phase trial, so results may not apply broadly. The device's safety and effectiveness are still unproven, and there are inherent risks with opioid use.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • KK Women's and Children's Hospital

    Singapore, 229899, Singapore

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Other studies related to the condition(s) this trial covers.