Sickle cell Drug's brain benefits under the microscope

NCT ID NCT05018728

First seen Jan 10, 2026 · Last updated May 21, 2026 · Updated 20 times

Summary

This study looked at whether voxelotor, a drug that improves anemia in sickle cell disease, also helps the brain by improving blood flow and oxygen use. Researchers measured brain activity in children and young adults aged 4 to 30 with sickle cell anemia. The study was stopped early, but it aimed to understand if the drug reduces stress on the brain.

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Contacts and locations

Locations

  • Aflac Sickle Cell Comprehensive Clinics at Children's Healthcare of Atlanta, Scottish Rite

    Atlanta, Georgia, 30342, United States

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.