New pill may stop painful ulcers after liver banding procedure
NCT ID NCT07267260
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether vonoprazan, a stomach acid blocker, can prevent ulcers that often form after endoscopic variceal band ligation (EVBL) in people with liver cirrhosis. About 154 adults will take either vonoprazan or a placebo daily for 14 days after the procedure. Researchers will check for ulcers with a follow-up endoscopy and track symptoms like pain and swallowing difficulty.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
vonoprazan
What this could lead to
If it works, this could offer a simple daily pill to prevent painful ulcers and bleeding after a common procedure for liver cirrhosis patients.
What could go wrong
This is a small, early-phase study with only 154 participants. The results may not apply to all patients, and vonoprazan might not work better than placebo.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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King Edward Medical University/Mayo Hospital
RECRUITINGLahore, Punjab Province, 54000, Pakistan
Contact Phone: •••-•••-•••• Email: •••••@•••••