New acid blocker may outperform standard drug for Post-POEM reflux healing

NCT ID NCT06955520

Recruiting now Disease control Sponsor: Asian Institute of Gastroenterology, India Source: ClinicalTrials.gov ↗

First seen Apr 30, 2026 · Last updated May 18, 2026 · Updated 5 times

Summary

This study tests whether Vonaprazan, a newer acid blocker, works better than the standard drug Esomeprazole for healing moderate-to-severe esophagitis caused by acid reflux after POEM surgery for achalasia. About 300 adults who had POEM and developed reflux esophagitis will take one of the two drugs for 8 weeks. The main goal is to see which drug heals the esophagus better, as seen on endoscopy.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Asian Institute of Gastroenterology /Aig Hospitals
RECRUITING

Hyderabad, Telangana, 500082, India

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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GERD