New drug tested to slow kidney damage in rare genetic disease

NCT ID NCT06425055

Summary

This study tested whether a drug called vonafexor is safe and can help protect kidney function in people with Alport syndrome, a genetic condition that damages the kidneys over time. It involved 26 patients who were at risk of their disease getting worse. Participants took the drug for 24 weeks while researchers checked for side effects and measured changes in key kidney health markers.

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Contacts and locations

Locations

  • Dr Anjay Rastogi - UCLA Health, David Geffen School of Medicine

    Los Angeles, California, 90095, United States

  • Dr Ankit Mehta - Renal Disease Research Institute

    Dallas, Texas, 75126, United States

  • Dr Arnold Silva - Boise Kidney & Hypertension

    Boise, Idaho, 83703, United States

  • Dr Eric Wallace - University of Alabama

    Birmingham, Alabama, 35294, United States

  • Dr James Simon - Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • Dr Moglie Le Quintrec - Hopital Lapeyronie

    Montpellier, 34090, France

  • Dr Suneel Udani - NANI Research

    Hinsdale, Illinois, 60521, United States

  • Dr Tingting Li - Washington University

    St Louis, Missouri, 63110, United States

  • Fundacio Puigvert

    Barcelona, 08025, Spain

  • Fundacion Jimenez Diaz

    Madrid, 28040, Spain

  • Hospital Virgen de la Arrixaca

    El Palmar, 30120, Spain

  • Pr Claire Rigothier - CHU De Bordeaux

    Bordeaux, 33076, France

  • Pr. Bertrand Knebelmann - Necker Enfants Malades

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.