New drug shows promise for slowing kidney decline in alport syndrome
NCT ID NCT06425055
First seen Feb 10, 2026 · Last updated May 15, 2026 · Updated 10 times
Summary
This study tested a drug called vonafexor in 26 people with Alport syndrome, a genetic condition that damages kidneys. The goal was to see if the drug is safe and can help slow down kidney function loss. Participants took different doses of the drug, and researchers measured side effects and changes in kidney function over time.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dr Anjay Rastogi - UCLA Health, David Geffen School of Medicine
Los Angeles, California, 90095, United States
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Dr Ankit Mehta - Renal Disease Research Institute
Dallas, Texas, 75126, United States
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Dr Arnold Silva - Boise Kidney & Hypertension
Boise, Idaho, 83703, United States
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Dr Eric Wallace - University of Alabama
Birmingham, Alabama, 35294, United States
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Dr James Simon - Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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Dr Moglie Le Quintrec - Hopital Lapeyronie
Montpellier, 34090, France
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Dr Suneel Udani - NANI Research
Hinsdale, Illinois, 60521, United States
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Dr Tingting Li - Washington University
St Louis, Missouri, 63110, United States
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Fundacio Puigvert
Barcelona, 08025, Spain
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Fundacion Jimenez Diaz
Madrid, 28040, Spain
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Hospital Virgen de la Arrixaca
El Palmar, 30120, Spain
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Pr Claire Rigothier - CHU De Bordeaux
Bordeaux, 33076, France
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Pr. Bertrand Knebelmann - Necker Enfants Malades
Paris, 75015, France
Conditions
Explore the condition pages connected to this study.