New study tests gentler breathing support for tiny preemies

NCT ID NCT05144724

Completed Knowledge-focused Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested two ways to help premature babies breathe right after birth: volume-targeted ventilation (giving a set amount of air) versus pressure-targeted ventilation (giving air at a set pressure). The study included 52 infants born between 23 and 28 weeks of pregnancy. The main goal was to see if the volume-targeted method could be used correctly in the delivery room without switching to the other method.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could show that volume-targeted ventilation is feasible in the delivery room, potentially leading to better breathing support for premature babies.
What could go wrong: This is a small pilot study with only 52 infants, so results may not apply to all preterm babies. The trial focuses on feasibility, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

newborn respiratory distress syndrome Pulmonary Atelectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEONATAL RESPIRATORY DISTRESS

Contacts and locations

Locations

Royal Alexandra Hospital

Edmonton, Alberta, T5H 3V9, Canada

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