New drug could keep cervical cancer at bay after chemo and radiation

NCT ID NCT06079671

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 23 times

Summary

This study tests a new medicine called volrustomig in women with high-risk cervical cancer that hasn't spread after standard chemoradiation. About 800 women will receive either volrustomig or a placebo to see if the drug can delay cancer growth and improve survival. The goal is to better control the disease and prevent it from coming back.

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Contacts and locations

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Study contacts

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Locations

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Birmingham, Alabama, 35233, United States
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Phoenix, Arizona, 85016, United States
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Tucson, Arizona, 85711, United States
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Little Rock, Arkansas, 72205, United States
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La Jolla, California, 92093, United States
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West Hollywood, California, 90048, United States
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Atlanta, Georgia, 30322, United States
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Augusta, Georgia, 30912, United States
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Savannah, Georgia, 31405, United States
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Melrose Park, Illinois, 60160, United States
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Indianapolis, Indiana, 46202, United States
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New Orleans, Louisiana, 70112, United States
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New Orleans, Louisiana, 70121, United States
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Shreveport, Louisiana, 71103, United States
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New York, New York, 10016, United States
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Syracuse, New York, 13210, United States
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Cleveland, Ohio, 44195, United States
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Columbus, Ohio, 43210, United States
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Eugene, Oregon, 97401, United States
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Philadelphia, Pennsylvania, 19107, United States
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Providence, Rhode Island, 02905, United States
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Dallas, Texas, 75390, United States
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Fort Worth, Texas, 76104, United States
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Houston, Texas, 77030, United States
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Tyler, Texas, 75702, United States
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Charlottesville, Virginia, 22908, United States
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Fairfax, Virginia, 22031, United States
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Richmond, Virginia, 23298, United States
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Barretos, 14784-400, Brazil
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Belo Horizonte, 30130-100, Brazil
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Curitiba, 80730-150, Brazil
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Fortaleza, 60336-045, Brazil
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Fortaleza, 60430-230, Brazil
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Goiânia, 74110-060, Brazil
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Natal, 59075-740, Brazil
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Porto Alegre, 90570-060, Brazil
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Porto Alegre, 90619-900, Brazil
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Porto Alegre, 98850-170, Brazil
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Porto Velho, 76834-899, Brazil
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Recife, 52010-075, Brazil
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Rio de Janeiro, 20220-410, Brazil
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Salvador, 40050 410, Brazil
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São Paulo, 01246-000, Brazil
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São Paulo, 01323-000, Brazil
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São Paulo, 1323001, Brazil
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Teresina, 64049-200, Brazil
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Hamilton, Ontario, L8V 1C3, Canada
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London, Ontario, N6A 5W9, Canada
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Toronto, Ontario, M4N 3M5, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Montreal, Quebec, H2X 0C1, Canada
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Montreal, Quebec, H3G 1A4, Canada
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Ste-Foy, Quebec, G1V 4G2, Canada
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Beijing, 100026, China
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Beijing, 100142, China
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Beijing, 100730, China
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Changde, 415000, China
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Changsha, 410008, China
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Changsha, 410013, China
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Chengdu, 610041, China
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Chengdu, 610044, China
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Chongqing, 400030, China
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Fuzhou, 350014, China
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Ganzhou, 341000, China
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Guangzhou, 510060, China
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SUSPENDED

Guangzhou, 510120, China
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Hangzhou, 310022, China
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Harbin, 150081, China
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Kunming, 650118, China
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Lanzhou, 730000, China
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Lanzhou, 730050, China
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Linyi, 276001, China
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Luzhou, 646000, China
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Nanchang, 330006, China
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Nanchang, 330029, China
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Shandong, China
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Shanghai, 200032, China
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Shanghai, 200080, China
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Shenyang, 110004, China
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Shenzhen, 518036, China
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Shenzhen, 518116, China
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Tianjin, 300060, China
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Wuhan, 430022, China
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Wuhan, 430030, China
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Xi'an, 710061, China
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Yibin, 610500, China
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Yinchuan, 750004, China
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Zhengzhou, 450008, China
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Zhengzhou, 450052, China
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Zhuzhou, 412007, China
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Aarhus N, 8200, Denmark
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København Ø, 2100, Denmark
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Odense, 5000, Denmark
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Berlin, 13353, Germany
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Bonn, 53127, Germany
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Hamburg, 20246, Germany
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Leipzig, 04103, Germany
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Calicut, 673601, India
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Jaipur, 302017, India
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Lucknow, 226003, India
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Madurai, 625107, India
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Mohali, 160055, India
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Nagpur, 440001, India
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Nashik, 422009, India
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Nashik, 422011, India
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New Delhi, 11029, India
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Vadodara, 391760, India
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Bari, 70124, Italy
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Bologna, 40138, Italy
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Catania, 95126, Italy
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Florence, 50141, Italy
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Lecco, 23900, Italy
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Milan, 20133, Italy
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Milan, 20141, Italy
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Milan, 20159, Italy
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Monza, 20900, Italy
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Naples, 80131, Italy
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Roma, 161, Italy
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Rome, 00168, Italy
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Turin, 10128, Italy
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Fukuoka, 812-8582, Japan
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Ginowan-shi, 901-2725, Japan
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Hidaka-shi, 350-1298, Japan
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Kagoshima, 890-8520, Japan
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Kōtoku, 135-8550, Japan
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Kurume-shi, 830-0011, Japan
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Maebashi, 371-8511, Japan
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Matsuyama, 791-0280, Japan
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Morioka, 028-3695, Japan
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Nagoya, 464-8681, Japan
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Osaka, 541-8567, Japan
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Sapporo, 003-0804, Japan
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Sapporo, 060-8638, Japan
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Shinjuku-ku, 160-8582, Japan
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Suita-shi, 565-0871, Japan
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Sunto-gun, 411-8777, Japan
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Toon-Shi, 791-0295, Japan
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Coyoacán, 04380, Mexico
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Culiacán, 80040, Mexico
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Guadalajara, 44650, Mexico
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Guadalajra, 44260, Mexico
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Mexico City, 03240, Mexico
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México, 04700, Mexico
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México, 14080, Mexico
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Monterrey, 64460, Mexico
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Oslo, 424, Norway
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Trondheim, 7030, Norway
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Concepción, 12125, Peru
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Lima, 15036, Peru
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Lima, 15038, Peru
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Lima, 15102, Peru
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Lima, LIMA 29, Peru
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Lima, Lima 34, Peru
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Lima, Lima39, Peru
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Bialystok, 15-027, Poland
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Gdansk, 80-214, Poland
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Gliwice, 44-101, Poland
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Krakow, 30-348, Poland
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Lodz, 90-513, Poland
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Poznan, 61-866, Poland
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Warsaw, 02-781, Poland
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Wroclaw, 53-413, Poland
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San Juan, 00927, Puerto Rico
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Daegu, 42601, South Korea
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Goyang-si, 10408, South Korea
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Gyeonggi-do, 13605, South Korea
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Seoul, 03080, South Korea
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Seoul, 03722, South Korea
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Seoul, 06351, South Korea
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Seoul, 5505, South Korea
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A Coruña, 15009, Spain
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Barcelona, 08036, Spain
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Barcelona, 8035, Spain
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Córdoba, 14004, Spain
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Girona, 17007, Spain
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Hospitalet deLlobregat, 08907, Spain
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Madrid, 28034, Spain
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Madrid, 28040, Spain
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Madrid, 28041, Spain
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Madrid, 28046, Spain
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Palma de Mallorca, 07010, Spain
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Valencia, 46009, Spain
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Valencia, 46010, Spain
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Changhua, 50006, Taiwan
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Kaohsiung City, 81362, Taiwan
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Kaohsiung City, 833, Taiwan
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New Taipei City, 220, Taiwan
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Taichung, 40447, Taiwan
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Taichung, 40705, Taiwan
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Tainan, 704, Taiwan
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Taipei, 10449, Taiwan
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Taipei, 11217, Taiwan
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Taoyuan, 333, Taiwan
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Bangkok, 10330, Thailand
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Bangkok, 10400, Thailand
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Bangkok, 10700, Thailand
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Muang, 50200, Thailand
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Udon Thani, 41330, Thailand
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Adana, 01250, Turkey (Türkiye)
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Ankara, 06100, Turkey (Türkiye)
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Ankara, 06490, Turkey (Türkiye)
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Cordaleo, 35575, Turkey (Türkiye)
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Istanbul, 32098, Turkey (Türkiye)
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Istanbul, 34214, Turkey (Türkiye)

Conditions

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LOCALLY ADVANCED CERVICAL CANCER