Lupus kidney drug for teens shows promise, but trial cut short
NCT ID NCT05288855
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a drug called voclosporin in teenagers with lupus nephritis, a kidney disease caused by lupus. The goal was to see if it could improve kidney function better than a placebo. Only 9 teens took part before the study was stopped early, so we don't have clear answers yet. The results may still help researchers design better future studies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Voclosporin (a drug that calms the immune system)
- What this could lead to
- If it works, this could point toward a treatment option for teenagers with lupus kidney disease.
- What could go wrong
- The trial was terminated early with only 9 participants, so results are very limited. Voclosporin may not work better than standard care and can have side effects like kidney problems or infections.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centro de Especialidades Medicas del Sureste
Mérida, Yucatán, 97000, Mexico
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Clinica de la Costa S.A.S
Barranquilla, Atlántico, 76100, Colombia
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Hospital Infantil de México Federico Gómez
Mexico City, Mexico
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Nemours Children's Hospital, Orlando
Orlando, Florida, 13535, United States
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Siriraj Hospital
Bangkok, 10700, Thailand
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Yokohama City University Hospital
Yokohama, Kanagawa, Japan
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