Lupus kidney drug for teens shows promise, but trial cut short
NCT ID NCT05288855
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a drug called voclosporin in teenagers with lupus nephritis, a kidney disease caused by lupus. The goal was to see if it could improve kidney function better than a placebo. Only 9 teens took part before the study was stopped early, so we don't have clear answers yet. The results may still help researchers design better future studies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Voclosporin (a drug that calms the immune system)
What this could lead to
If it works, this could point toward a treatment option for teenagers with lupus kidney disease.
What could go wrong
The trial was terminated early with only 9 participants, so results are very limited. Voclosporin may not work better than standard care and can have side effects like kidney problems or infections.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centro de Especialidades Medicas del Sureste
Mérida, Yucatán, 97000, Mexico
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Clinica de la Costa S.A.S
Barranquilla, Atlántico, 76100, Colombia
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Hospital Infantil de México Federico Gómez
Mexico City, Mexico
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Nemours Children's Hospital, Orlando
Orlando, Florida, 13535, United States
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Siriraj Hospital
Bangkok, 10700, Thailand
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Yokohama City University Hospital
Yokohama, Kanagawa, Japan