Lupus kidney drug tested in kids – but study stopped early

NCT ID NCT05962788

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at the long-term safety of the drug voclosporin in adolescents and children with lupus nephritis, a kidney disease caused by lupus. Participants took voclosporin capsules twice daily along with standard medications. The trial was terminated early and only enrolled 4 people, so the results are very limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

voclosporin

What this could lead to

If successful, this could show that voclosporin is safe and effective for long-term use in young people with lupus nephritis.

What could go wrong

The trial was terminated early and enrolled only 4 participants, so results are very limited. It is unclear if voclosporin offers benefits over standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lupus nephritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centro de Especialidades Medicas del Sureste

    Mérida, Yucatán, 97000, Mexico

  • Clinica de la Costa S.A.S

    Barranquilla, Atlántico, 76100, Colombia

  • Hospital Infantil de México Federico Gómez

    Mexico City, 06720, Mexico

  • Siriraj Hospital

    Bangkok, 10700, Thailand

  • UNC-Chapel Hill

    Chapel Hill, North Carolina, 27514, United States

  • Yokohama City University Hospital

    Yokohama, Kanagawa, Japan