New malaria vaccine vivaxin enters first human tests

NCT ID NCT07172724

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-stage trial is testing a new vaccine called Vivaxin, designed to protect against malaria caused by the Plasmodium vivax parasite. Researchers will give the vaccine to 48 healthy adults who have never had malaria, to check if it is safe and whether it triggers an immune response. The study is not yet recruiting and will compare the vaccine against a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vivaxin vaccine (a lyophilized antigen mixed with an adjuvant called CTVad)

What this could lead to

If successful, this could lead to a vaccine that prevents malaria caused by Plasmodium vivax, a major cause of illness worldwide.

What could go wrong

This is a very early Phase 1 trial with only 48 people, so it is primarily checking safety and immune response, not whether the vaccine actually prevents malaria. Many vaccines fail at this stage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malaria Plasmodium vivax malaria prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centro de Pesquisas Clínicas (CPC) do Hospital das Clínicas (HC) da UFMG/ Filial Ebserh

    Belo Horizonte, Minas Gerais, 30130-100, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••