Major trial tests promising pill to restore skin color in vitiligo

NCT ID NCT06118411

Ongoing Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study is testing if a daily pill called upadacitinib can help repigment skin in people with non-segmental vitiligo, an autoimmune condition that causes white patches. About 614 participants will be randomly assigned to receive either the active drug or a placebo pill for 48 weeks, followed by the active drug for everyone. The main goals are to see if the treatment safely reduces the total area of vitiligo and improves repigmentation on the face.

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Contacts and locations

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Locations

ASST degli Spedali Civili di Brescia /ID# 259772

Brescia, 25123, Italy
Advanced Clinical Research Institute /ID# 260058

Tampa, Florida, 33607, United States
Advanced Research Associates - Glendale /ID# 259915

Glendale, Arizona, 85308, United States
Ajou University Hospital /ID# 260916

Suwon, Gyeonggido, 16499, South Korea
Alliance Dermatology and Mohs Center /ID# 259926

Phoenix, Arizona, 85032, United States
Ambulatory for Specialized Medical Care-IPSMC-skin and venereal diseases /ID# 259955

Sofiya, Sofia, 1407, Bulgaria
Amphia Ziekenhuis /ID# 259696

Breda, North Brabant, 4818 CK, Netherlands
Amsterdam UMC, locatie AMC /ID# 259676

Amsterdam, North Holland, 1105 AZ, Netherlands
Apex Clinical Trials /ID# 260096

Brandon, Florida, 33511, United States
Beijing Tongren Hospital Affiliated To Capital Medical University /ID# 260919

Beijing, Beijing Municipality, 100730, China
Bellaire Dermatology Associates /ID# 260044

Bellaire, Texas, 77401, United States
Bravis Ziekenhuis /ID# 259501

Bergen op Zoom, North Brabant, 4624 VT, Netherlands
Brunswick Dermatology Center /ID# 260237

Fredericton, New Brunswick, R3M 3Z4, Canada
Buenos Aires Skin /ID# 259885

Ciudad Autonoma de Buenos Aire, Buenos Aires F.D., 1055, Argentina
CHU Toulouse - Hopital Larrey /ID# 259445

Toulouse, Haute-Garonne, 31400, France
CHU de Liege /ID# 259427

Liège, 4000, Belgium
Centre Hospitalier Universitaire de Bordeaux - Groupe Hospitalier Saint-Andre /ID# 259443

Bordeaux, Gironde, 33000, France
Centre de Recherche dermatologique du Quebec Metropolitain /ID# 260241

Québec, Quebec, G1V 4X7, Canada
Centro de Investigacion y Prevencion Cardiovascular (CIPREC) /ID# 259889

Buenos Aires, 1061, Argentina
Centrum Medyczne Angelius Provita /ID# 259752

Katowice, Silesian Voivodeship, 40-615, Poland
Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 260294

Berlin, 10117, Germany
Chengdu Second Municipal People's Hospital /ID# 260423

Chengdu, Sichuan, 610017, China
Chu de Nice-Hopital L'Archet Ii /Id# 259442

Nice, Alpes-Maritimes, 06202, France
Chungnam National University Hospital /ID# 260917

Daejeon, Daejeon Gwang Yeogsi, 35015, South Korea
Clarkston Dermatology /ID# 260069

Clarkston, Michigan, 48346, United States
Cleaver Medical Group Dermatology /ID# 259925

Dawsonville, Georgia, 30534, United States
ClinOhio Research Services /ID# 260300

Columbus, Ohio, 43213-4440, United States
Clinical Trials Research Institute /ID# 259910

Thousand Oaks, California, 91320-2130, United States
Cliniques Universitaires UCL Saint-Luc /ID# 259429

Brussels, Brussels Capital, 1200, Belgium
Consorci Hospital General Universitario de Valencia /ID# 259372

Valencia, 46014, Spain
DERMA-B Egeszsegugyi es Szolgaltato - Debrecen - Gyepusor Utca /ID# 260072

Debrecen, 4031, Hungary
Dawes Fretzin, LLC /ID# 260068

Indianapolis, Indiana, 46256, United States
DeNova Research /ID# 260611

Chicago, Illinois, 60610, United States
DermResearchCenter of New York, Inc. /ID# 259906

Stony Brook, New York, 11790, United States
Derma therapy spol /ID# 260838

Bratislava, Bratislava Region, 851 01, Slovakia
Dermatologie Mahlow /ID# 260148

Blankenfelde-Mahlow, Brandenburg, 15831, Germany
Dermatology Clinical Research Center of San Antonio /ID# 260047

San Antonio, Texas, 78229, United States
Dermatology Hospital of Southern Medical University /ID# 260136

Guangzhou, Guangdong, 510091, China
Dermatology Research Associates /ID# 260056

Los Angeles, California, 90045, United States
Dermatology Research Institute - Blackfoot Trail /ID# 261175

Calgary, Alberta, T2J 7E1, Canada
Dermatology Treatment and Research Center /ID# 260078

Dallas, Texas, 75230, United States
Dermatology and Ophthalmology Kume Clinic /ID# 260555

Sakai-shi, Osaka, 593-8324, Japan
Dermodent Centrum Medyczne Aldona Czajkowska Rafał Czajkowski /ID# 259690

Osielsko, Kuyavian-Pomeranian Voivodeship, 86-031, Poland
Diagnosis - Consult Centre 20 - Sofia /ID# 259953

Sofiya, Sofia, 1618, Bulgaria
Diagnostic Consultative Centre (Dcc) - Foкus 5 /ID# 259956

Sofiya, Sofia, 1463, Bulgaria
Direct Helpers Research Center /ID# 259932

Hialeah, Florida, 33012, United States
Dr. Chih-ho Hong Medical Inc. /ID# 260239

Surrey, British Columbia, V3R 6A7, Canada
Dr. Samuel Sanchez PSC /ID# 260090

Caguas, 00727, Puerto Rico
Dre Angelique Gagne-Henley M.D. inc. /ID# 260238

Saint-Jérôme, Quebec, J7Z 7E2, Canada
Duplicate_Stanford University /ID# 260081

Redwood City, California, 94063, United States
Encore Medical Research - Weston /ID# 260542

Weston, Florida, 33331, United States
Encore Medical Research /ID# 259963

Hollywood, Florida, 33021, United States
Fachklinik Bad Bentheim /ID# 260293

Bad Bentheim, Lower Saxony, 48455, Germany
Fakultna nemocnica Trnava /ID# 260164

Trnava, 917 02, Slovakia
First Affiliated Hospital of Kunming Medical University /ID# 260017

Kunming, Yunnan, 650032, China
Florida Academic Dermatology Center /ID# 259919

Coral Gables, Florida, 33134-5755, United States
GSI Clinical Research, LLC /ID# 259918

Margate, Florida, 33063, United States
Grand Hôpital de Charleroi - Les Viviers /ID# 259437

Charleroi, Hainaut, 6280, Belgium
Great Lakes Research Group - Bay City /ID# 260600

Bay City, Michigan, 48706, United States
Grupo Pedro Jaen /ID# 259375

Madrid, 28006, Spain
HCL - Hopital Edouard Herriot /ID# 259444

Lyon, Rhone, 69003, France
Hadassah Medical Center-Hebrew University /ID# 259849

Jerusalem, Jerusalem, 91120, Israel
Hamzavi Dermatology - Canton /ID# 260545

Canton, Michigan, 48187, United States
Hangzhou Third People'S Hospital /ID# 261005

Hangzhou, Zhejiang, 310009, China
Henry Ford Medical Center - New Center One /ID# 260059

Detroit, Michigan, 48202-3046, United States
Hopitaux Universitaires Henri Mondor - Hopital Henri Mondor /ID# 259446

Créteil, Paris, 94010, France
Hospital CUF Descobertas /ID# 259788

Lisbon, 1998-018, Portugal
Hospital Clinico Universitario Lozano Blesa /ID# 259373

Zaragoza, 50009, Spain
Hospital Universitario Clinico San Cecilio /ID# 259374

Granada, 18016, Spain
Hospital Universitario Germans Trias i Pujol /ID# 259371

Badalona, Barcelona, 08916, Spain
Hospital Universitario Quironsalud Madrid /ID# 259377

Pozuelo de Alarcón, Madrid, 28223, Spain
Hospital Universitario de Getafe /ID# 259376

Getafe, Madrid, 28905, Spain
Huashan Hospital, Fudan University /ID# 259823

Shanghai, Shanghai Municipality, 200040, China
IRCCS Istituti Fisioterapici Ospitalieri-Istituto Dermatologico San Gallicano /ID# 259771

Rome, Roma, 00144, Italy
Icahn School of Medicine at Mount Sinai /ID# 259909

New York, New York, 10029, United States
Indiana University Health University Hospital /ID# 259974

Indianapolis, Indiana, 46202, United States
Innovative Dermatology - Plano /ID# 260628

Plano, Texas, 75024, United States
Instituto De Investigaciones Clínicas Córdoba /ID# 260371

Córdoba, Córdoba Province, 5000, Argentina
Instituto de Neumonologia y Dermatologia /ID# 259888

Ciudad Autonoma de Buenos Aire, Buenos Aires F.D., 1425, Argentina
Integrative Skin Science and Research /ID# 260060

Sacramento, California, 95815, United States
Klinika Ambroziak Dermatologia /ID# 260018

Warsaw, Masovian Voivodeship, 02-953, Poland
Klinika Osipowicz & Turkowski sp.z.o.o /ID# 259761

Warsaw, Masovian Voivodeship, 00-716, Poland
Klinikum rechts der Isar /ID# 260291

Munich, Bavaria, 81675, Germany
Krakowskie Centrum Medyczne /ID# 261424

Krakow, Lesser Poland Voivodeship, 31-501, Poland
Kyung Hee University Hospital at Gangdong /ID# 260879

Seoul, Seoul Teugbyeolsi, 05278, South Korea
LEADER Research /ID# 260407

Hamilton, Ontario, L8L 3C3, Canada
Life Clinical Trials /ID# 260097

Margate, Florida, 33063, United States
MVZ Dermatologisches Zentrum Bonn GmbH /ID# 260287

Bonn, Hesse, 53111, Germany
Malopolskie Centrum Kliniczne /ID# 259686

Krakow, Lesser Poland Voivodeship, 30-149, Poland
Medical Center Cordis /ID# 259954

Pleven, 5800, Bulgaria
Medical University of South Carolina /ID# 259916

Charleston, South Carolina, 29425, United States
Mindful Medical Research /ID# 260092

San Juan, 00918-3756, Puerto Rico
Minnesota Clinical Study Center /ID# 260154

New Brighton, Minnesota, 55112, United States
Nagoya City University Hospital /ID# 260551

Nagoya, Aichi-ken, 467-8602, Japan
Nippon Medical School Hospital /ID# 260550

Bunkyo-ku, Tokyo, 113-8603, Japan
Oakland Hills Dermatology /ID# 260602

Auburn Hills, Michigan, 48326, United States
Oregon Dermatology and Research Center /ID# 259917

Portland, Oregon, 97210, United States
Oregon Medical Research Center /ID# 259911

Portland, Oregon, 97201, United States
Osteo Medic s.c. Artur Racewicz Jerzy Supronik /ID# 259753

Bialystok, Podlaskie Voivodeship, 15-351, Poland
Private Practice - Dr. Abdou Zarzour /ID# 260290

Halle, Saxony-Anhalt, 06108, Germany
Private Practice - Dr. Kim Papp Clinical Research /ID# 260406

Waterloo, Ontario, N2J 1C4, Canada
Private Practice - Dr. Tooraj Raoof /ID# 260055

Encino, California, 91436, United States
Progressive Clinical Research /ID# 260070

San Antonio, Texas, 78229, United States
Psoriahue Med Interdisciplinar /ID# 259890

Ciudad Autonoma de Buenos Aire, Buenos Aires F.D., 1425, Argentina
Rabin Medical Center /ID# 260420

Petah Tikva, 4941492, Israel
Rambam Health Care Campus /ID# 259852

Haifa, 3109601, Israel
Renmin Hospital of Wuhan University /ID# 260477

Wuhan, Hubei, 430060, China
Royalderm Agnieszka Nawrocka /ID# 259691

Warsaw, Masovian Voivodeship, 02-962, Poland
Sanatorio 9 de Julio /ID# 260245

San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Santa Cruz Behavioral (SCB) Research Center /ID# 260100

Bayamón, 00961-6910, Puerto Rico
Savin Medical Group, LLC /ID# 259968

Miami Lakes, Florida, 33014, United States
Schweiger Dermatology, P.C. /ID# 260152

New York, New York, 07044-2946, United States
Second Affiliated Hospital of Xian Jiaotong University /ID# 260011

Xi'an, Shaanxi, 710004, China
Shandong Dermatological Hospital /ID# 260338

Jinan, Shandong, 250022, China
Sir Run Run Shaw Hospital Zhejiang University School of Medicine /ID# 260626

Hangzhou, Zhejiang, 310020, China
Skin Care Research - Hollywood /ID# 260101

Hollywood, Florida, 33021-6748, United States
Skin Care Research Boca Raton /ID# 260094

Boca Raton, Florida, 33486-2269, United States
Soon Chun Hyang University Hospital Bucheon /ID# 260836

Bucheon-si, Gyeonggido, 14584, South Korea
Specjalistyczny Gabinet Dermatologiczny Aplikacyjno Badawczy /ID# 260016

Krakow, Lesser Poland Voivodeship, 30-002, Poland
Tel Aviv Sourasky Medical Center /ID# 259850

Tel Aviv, Tel Aviv, 6423906, Israel
The Catholic University Of Korea St. Vincent's Hospital /ID# 260880

Suwon, Gyeonggido, 16247, South Korea
The Chaim Sheba Medical Center /ID# 259851

Ramat Gan, Tel Aviv, 5265601, Israel
The First Affiliated Hospital of Wenzhou Medical University /ID# 259822

Wenzhou, Zhejiang, 325000, China
The First Affiliated Hospital of Xi'an Jiaotong University /ID# 260340

Xi'an, Shaanxi, 710061, China
The Second Affiliated Hospital of Guangzhou Medical University /ID# 259929

Guangzhou, Guangdong, 510260, China
The University of Osaka Hospital /ID# 261285

Suita-shi, Osaka, 565-0871, Japan
Tianjin Medical University General Hospital /ID# 259812

Tianjin, Tianjin Municipality, 300052, China
Tokyo Medical University Hospital /ID# 260552

Shinjuku-ku, Tokyo, 160-0023, Japan
Tufts Medical Center /ID# 260088

Boston, Massachusetts, 02111-1552, United States
Twoja Przychodnia SCM /ID# 259757

Szczecin, West Pomeranian Voivodeship, 71-434, Poland
UMass Memorial Medical Center /ID# 259921

Worcester, Massachusetts, 01605, United States
UZ Gent /ID# 259430

Ghent, Oost-Vlaanderen, 9000, Belgium
Unidade Local de Saude da Regiao de Leiria, EPE /ID# 259789

Leiria, 2410-197, Portugal
Unidade Local de Saude de Coimbra, EPE /ID# 259793

Coimbra, 3000-075, Portugal
Unidade Local de Saude de Santo Antonio, E.P.E. /ID# 259791

Porto, 4099-003, Portugal
Universitaetsklinikum Carl Gustav Carus Dresden /ID# 260289

Dresden, Saxony, 01307, Germany
Universitaetsklinikum Erlangen /ID# 260153

Erlangen, Bavaria, 91054, Germany
Universitaetsklinikum Frankfurt /ID# 260288

Frankfurt am Main, Hesse, 60590, Germany
Universitaetsklinikum Muenster /ID# 260147

Münster, North Rhine-Westphalia, 48149, Germany
Universitaetsmedizin Mainz /ID# 260151

Mainz, Rhineland-Palatinate, 55131, Germany
University of California Davis Health /ID# 260062

Sacramento, California, 95817, United States
University of California Irvine /ID# 260080

Irvine, California, 92697-1385, United States
Vitiligo & Pigmentation Institute of Southern California /ID# 259970

Los Angeles, California, 90036-5679, United States
Vivida Dermatology- Flamingo /ID# 260609

Las Vegas, Nevada, 89119-5190, United States
West China Hospital, Sichuan University /ID# 260624

Chengdu, Sichuan, 610041, China
Wiseman Dermatology Research /ID# 260236

Winnipeg, Manitoba, R3M 3Z4, Canada
Yamagata University Hospital /ID# 260553

Yamagata, Yamagata, 990-9585, Japan
Yamanashi Prefectural Central Hospital /ID# 260554

Kofu, Yamanashi, 400-8506, Japan

Conditions

Explore the condition pages connected to this study.

VITILIGO