Can a vitamin D2 blast speed up recovery in lymphoma patients?

NCT ID NCT07366450

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a high-intensity loading dose of vitamin D2 to standard weekly dosing in 52 patients with newly diagnosed aggressive non-Hodgkin lymphoma who are also receiving standard chemotherapy. The goal is to see if the high-dose approach normalizes vitamin D levels faster and safely. Participants will be randomly assigned to one of the two dosing strategies and monitored for vitamin D levels, safety, and treatment outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ergocalciferol (vitamin D2)
What this could lead to
If successful, this could show a faster, safer way to correct vitamin D deficiency in lymphoma patients, potentially improving overall treatment outcomes.
What could go wrong
This is a small, early-stage trial with only 52 participants. The high-dose regimen may cause side effects like high calcium levels, and faster vitamin D normalization may not translate to better lymphoma control.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Phramonkutklao Hospital

    Bangkok, 10400, Thailand

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