Can a vitamin D2 blast speed up recovery in lymphoma patients?

NCT ID NCT07366450

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a high-intensity loading dose of vitamin D2 to standard weekly dosing in 52 patients with newly diagnosed aggressive non-Hodgkin lymphoma who are also receiving standard chemotherapy. The goal is to see if the high-dose approach normalizes vitamin D levels faster and safely. Participants will be randomly assigned to one of the two dosing strategies and monitored for vitamin D levels, safety, and treatment outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ergocalciferol (vitamin D2)

What this could lead to

If successful, this could show a faster, safer way to correct vitamin D deficiency in lymphoma patients, potentially improving overall treatment outcomes.

What could go wrong

This is a small, early-stage trial with only 52 participants. The high-dose regimen may cause side effects like high calcium levels, and faster vitamin D normalization may not translate to better lymphoma control.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aggressive B-cell non-Hodgkin lymphoma lymphoma, non-Hodgkin, familial non-Hodgkin lymphoma vitamin D deficiency vitamin D hydroxylation-deficient rickets, type 1B

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Phramonkutklao Hospital

    Bangkok, 10400, Thailand

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact