Could vitamin d help fight sepsis in preterm infants?

NCT ID NCT07245277

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving vitamin D alongside antibiotics helps premature babies with sepsis recover better. Researchers gave 78 preterm infants either antibiotics alone or antibiotics plus 400 or 800 IU of vitamin D daily for 7 days. They tracked changes in sepsis scores and C-reactive protein levels to see if vitamin D made a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vitamin D (cholecalciferol)

What this could lead to

If it works, adding vitamin D to standard antibiotics could help reduce infection severity in preterm babies with sepsis.

What could go wrong

This is a small, completed Phase 4 trial with only 78 infants. Results may not apply to all preterm babies, and vitamin D may not provide significant benefit over antibiotics alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neonatal sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hasan Sadikin General Hospital

    Bandung, West Java, 40161, Indonesia

  • Rumah Sakit Umum Daerah Bandung Kiwari

    Bandung, West Java, 40233, Indonesia