Could vitamin d help fight sepsis in preterm infants?

NCT ID NCT07245277

Completed Disease control Sponsor: Universitas Padjadjaran Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving vitamin D alongside antibiotics helps premature babies with sepsis recover better. Researchers gave 78 preterm infants either antibiotics alone or antibiotics plus 400 or 800 IU of vitamin D daily for 7 days. They tracked changes in sepsis scores and C-reactive protein levels to see if vitamin D made a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vitamin D (cholecalciferol)
What this could lead to: If it works, adding vitamin D to standard antibiotics could help reduce infection severity in preterm babies with sepsis.
What could go wrong: This is a small, completed Phase 4 trial with only 78 infants. Results may not apply to all preterm babies, and vitamin D may not provide significant benefit over antibiotics alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NEONATAL SEPSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

neonatal sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEONATAL SEPSIS PRETERM INFANTS

Contacts and locations

Locations

Hasan Sadikin General Hospital

Bandung, West Java, 40161, Indonesia
Rumah Sakit Umum Daerah Bandung Kiwari

Bandung, West Java, 40233, Indonesia

More trials for these conditions

Other studies related to the condition(s) this trial covers.