Can High-Dose vitamin c injections ease symptoms of deficiency?
NCT ID NCT06983847
First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time
Summary
Researchers are observing how high-dose vitamin C injections affect symptoms and tolerability in adults with vitamin C deficiency caused by acute or chronic diseases. The study includes about 1,000 participants and tracks changes in general and disease-specific symptoms using a simple score. Doctors also give a global rating of how well the treatment works. The goal is to learn which patient groups use the product and which symptoms improve.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- high-dose vitamin C given as an injection
- What this could lead to
- If the injections help, doctors could have clearer guidance on when to use high-dose vitamin C for people with deficiency during acute or chronic illness.
- What could go wrong
- This is an observational study, so it cannot prove that vitamin C injections cause symptoms to improve. Symptoms may change for other reasons, and the results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2019
- Expected to finish
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Nov 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with a vitamin C deficiency due to acute or chronic underlying diseases
- Ages
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18 to 120 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with vitamin C deficiency * Age ≥ 18 years Exclusion Criteria: * Hypersensitivity to the active ingredient or any of the excipients * Oxalate urolithiasis * Iron storage disease (thalassemia, hemochromatosis, sideroblastic anemia) or recent red blood cell transfusion * Renal insufficiency * Glucose-6-phosphate dehydrogenase deficiency/defect * Pregnant/breastfeeding women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Multiple Physicians from Austria
RECRUITINGVienna, Etc., Austria, Austria
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