Vitamin c infusion trial aims to save lives after severe burns

NCT ID NCT04138394

Summary

This large international study is testing whether adding high-dose intravenous vitamin C to standard burn care helps patients recover better. It involves 666 adults with severe burns covering at least 20% of their body. Half will receive vitamin C infusions for four days alongside standard care, while the other half receives a placebo, to see if vitamin C reduces organ failure and improves survival.

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Contacts and locations

Locations

  • Arizona Burn Center Valleywise Health

    Phoenix, Arizona, 85008, United States

  • Ascension Columbia St. Mary's

    Milwaukee, Wisconsin, 53211, United States

  • BG Klinik Tübingen

    Tübingen, Baden-Wurttemberg, 72076, Germany

  • Belgium Military Hospital, Military Hospital

    Brussels, Belgium

  • Berufsgenossenschaftliche Unfallklinik Ludwigshafen

    Ludwigshafen, Germany

  • Bridgeport Hospital

    Bridgeport, Connecticut, 06610, United States

  • CHU de Québec-Université Laval, Hôpital de l'Enfant-Jésus

    Québec, Quebec, G1J 1Z4, Canada

  • Centre Hospitalier Universitaire de Liege

    Liège, Belgium

  • Centre de recherche du CHUM

    Montreal, Quebec, H2X 0A9, Canada

  • Centro Nacional del Quemado y Cirugías Reconstructivas

    Asunción, Paraguay

  • Chelsea and Westminster Hospital

    Chelsea, London, SW10 9NH, United Kingdom

  • Ghent University Hospital

    Ghent, Oost Vlaanderen, 9000, Belgium

  • Grand Hopital de Charleroi

    Charleroi, Hainaut, 6280, Belgium

  • Hamilton General Hospital, Hamilton Health Sciences Corporation

    Hamilton, Ontario, L8L 2X2, Canada

  • Harborview Medical Center - Seattle

    Seattle, Washington, 98104, United States

  • Hospital Central Dr. Ignacio Morones Prieto

    San Luis Potosí City, San Luis Potosí, 78290, Mexico

  • Hospital San Juan de Dios

    San José, Provincia de San José, Costa Rica

  • Klinikum St. George

    Leipzig, Saxony, 04129, Germany

  • MedStar Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

  • Mercy Hospital St. Louis

    St Louis, Missouri, 63141, United States

  • Merheim Medical Center, Hospitals of Cologne

    Cologne, Germany

  • QEII Health Sciences Centre

    Halifax, Nova Scotia, B3H 3A6, Canada

  • Queen Elizabeth Hospital Birmingham

    Birmingham, Mindelsohn Way, B15 2TH, United Kingdom

  • RWTH Aachen University, Aachen

    Aachen, Germany

  • Siriraj Hospital, Mahidol University

    Bangkok, Bangkok, 10700, Thailand

  • St Helens and Knowsley Hospitals NHS Trust

    Prescot, L35 5DR, United Kingdom

  • Sunnybrook Health Sciences Centre, Ross Tilley Burn Centre

    Toronto, Ontario, M4N 3M5, Canada

  • The Mid Yorkshire Hospitals NHS Trust

    Wakefield, United Kingdom

  • The Ohio State University Medical Center

    Ohio City, Ohio, 43210, United States

  • The University of Chicago Medical Center

    Chicago, Illinois, 60637, United States

  • University Hospital Würzburg

    Würzburg, Germany

  • University of Iowa Hospitals & Clinics

    Iowa City, Iowa, 52242, United States

  • University of Texas Health Science Center - Houston

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.