Can virtual reality reboot the brain after severe injury?

NCT ID NCT06474871

Completed Symptom relief Sponsor: Anna Estraneo Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This study tests whether virtual reality (VR) exercises can improve cognitive functions like attention and problem-solving in people with severe acquired brain injury. Twenty-eight participants will be randomly assigned to either VR-based cognitive training or traditional paper-and-pencil exercises. The goal is to see if VR offers a better way to recover thinking skills in the months after injury.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Virtual reality rehabilitation system (Khymeia VRRS)
What this could lead to: If it works, this could offer a more engaging and effective way to help people recover cognitive function after severe brain injury.
What could go wrong: This is a small early-stage trial with only 28 participants, so results may not apply to everyone. VR may not be better than traditional therapy, and some people may find it uncomfortable.

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Conditions

The condition(s) this trial relates to.

brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACQUIRED BRAIN INJURY

Contacts and locations

Locations

ICS Maugeri

Telese Terme, Benevento, 82037, Italy
ICS Maugeri

Bari, Italy
IRCCS Santa Maria Nascente Fondazione Don Gnocchi ONLUS

Milan, Milan, 20148, Italy
Ospedale Policlinico San Martino

Genova, Italy
Polo Specialistico Riabilitativo Fondazione Don Carlo Gnocchi ONLUS

Sant'Angelo dei Lombardi, Avellino, 83054, Italy

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