New drug combo shows promise for tough brain cancer

NCT ID NCT05211336

First seen Jan 11, 2026 · Last updated Jun 13, 2026 · Updated 25 times

Summary

This early-phase study tests a combination of five drugs (VIPOR) in 14 adults with aggressive B-cell lymphoma that has spread to the brain or spinal cord. The main goal is to see if the treatment is safe enough for patients to complete at least two 21-day cycles without serious side effects. Researchers also track whether tumors shrink or disappear. This is not a cure; patients may need ongoing management.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.