Could a cell shot free CML patients from daily pills?

NCT ID NCT07651878

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial tests a cell therapy called vididencel in 24 adults with chronic myeloid leukemia (CML) who still have traces of cancer despite taking standard medication. The goal is to see if adding vididencel to their current treatment is safe and might eventually allow them to lower or stop their daily pills. Participants receive injections over several months and are followed for up to 3 years.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
vididencel (a cell therapy made from donor cells)
What this could lead to
If it works, this could help some CML patients reduce or stop their daily TKI medication without the cancer returning.
What could go wrong
This is a very early Phase 1 trial with only 24 participants, so it may not work or could have side effects. Participants may not benefit directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic myelogenous leukemia, BCR-ABL1 positive Leukemia, Myelogenous, Chronic, BCR-ABL Positive

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Haukeland University Hospital

    RECRUITING

    Bergen, Norway

More trials for these conditions

Other studies related to the condition(s) this trial covers.