Could a tiny aspirin dose plus a blood thinner be safer for heart patients?

NCT ID NCT04990791

First seen Feb 22, 2026 · Last updated May 15, 2026 · Updated 13 times

Summary

This study looked at whether a very low dose of aspirin (20 mg twice daily) combined with a blood thinner called rivaroxaban (2.5 mg twice daily) works differently than standard treatments in people with chronic coronary syndromes. Forty-eight adults who already take daily aspirin for heart disease were given three different medication regimens in random order, each for two weeks. Researchers measured bleeding time, blood clotting, and inflammation markers to compare the new combo with standard aspirin alone or standard aspirin plus rivaroxaban.

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Contacts and locations

Locations

  • Sheffield Teaching Hospitals NHS Foundation Trust

    Sheffield, South Yorkshire, S5 7AU, United Kingdom

Conditions

Explore the condition pages connected to this study.