Can a standard 40 mm needle reach the hip muscle in people with higher BMI?
NCT ID NCT07827300
First seen Sep 18, 2026 · Last updated Sep 18, 2026
Summary
Researchers at Marmara University studied whether a 40 mm needle delivers medication into the ventrogluteal muscle in adults with a body mass index of 25 or higher. They used ultrasound to measure tissue thickness and watch the needle tip in real time during a vitamin B12 injection. The team checked how often the needle reached at least 10 mm below the muscle surface and stayed clear of the hip bone and sciatic nerve. They compared results across three body mass index groups.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- cyanocobalamin (vitamin B12) injected into the ventrogluteal muscle with a 40 mm needle
- What this could lead to
- If the 40 mm needle reliably reaches muscle in people with higher body mass index, nurses could use a standard needle length with more confidence and fewer repeat injections.
- What could go wrong
- This is a small measurement study, not a test of whether the injection works better. Results may not apply to other needle lengths, injection sites, or people with different body shapes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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89 people
The number who actually took part.
- Started
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Apr 2026
- Finished
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Aug 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \>18 and \<75 years. * Body mass index \>24.9 kg/m². * A clinical order for intramuscular administration of 1 mL cyanocobalamin at a concentration of 1000 mcg/mL. * No muscle atrophy or motor or sensory loss associated with neurological or muscular pathology. * Able to walk independently or with assistance and perform activities of daily living. Exclusion Criteria: * Degenerative muscle diseases or motor neuron diseases. * Amyotrophic lateral sclerosis or other progressive neuromuscular diseases. * Severe muscle atrophy or motor function loss that could affect the reliability of ultrasonographic muscle-thickness measurements. * Muscle structure considered unsuitable for reliable ultrasonographic measurement or presence of motor/sensory function loss on clinical evaluation.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Bagcilar Training and Research Hospital
Istanbul, Eyalet/Yerleşke, 34000, Turkey (Türkiye)
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