New drug cocktail shows promise for Hard-to-Treat lymphoma

NCT ID NCT04447716

First seen Oct 31, 2025 · Last updated May 10, 2026 · Updated 29 times

Summary

This early-phase study tests the safety and best dose of a three-drug combination (venetoclax, lenalidomide, and rituximab) in adults with follicular or marginal zone lymphoma that has returned or not responded to prior treatment. The drugs work by blocking cancer cell survival signals and boosting the immune system to attack the cancer. Only 4 participants were enrolled, so results are very preliminary.

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Contacts and locations

Locations

  • Sidney Kimmel Cancer Center at Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

Conditions

Explore the condition pages connected to this study.