New drug cocktail aims to wipe out leukemia more deeply

NCT ID NCT07228273

First seen Nov 15, 2025 · Last updated Apr 28, 2026 · Updated 20 times

Summary

This study tests whether adding venetoclax to a standard chemotherapy regimen (FLAG IDA) can achieve deeper remission in adults aged 18–65 with newly diagnosed acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome. About 102 participants will be randomly assigned to the new combination or standard treatment. The goal is to see if the new approach leads to a higher rate of complete remission with no detectable cancer cells.

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Contacts and locations

Locations

  • OHSU Knight Cancer Institute

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.