New combo aims to wipe out hidden leukemia cells in high-risk patients

NCT ID NCT03128879

First seen Nov 21, 2025 · Last updated May 21, 2026 · Updated 20 times

Summary

This study tests whether adding venetoclax to ongoing ibrutinib or acalabrutinib treatment can clear remaining leukemia cells in people with high-risk chronic lymphocytic leukemia (CLL). Participants must have been on ibrutinib or acalabrutinib for at least 12 months and still have detectable disease. The goal is to see if the combination can make the cancer undetectable in the bone marrow.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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