New combo offers hope for Tough-to-Treat leukemia

NCT ID NCT07451912

First seen Mar 12, 2026 · Last updated May 12, 2026 · Updated 8 times

Summary

This study tests a combination of three drugs (venetoclax, a hypomethylating agent, and low-dose cytarabine) in adults newly diagnosed with a specific genetic subtype of acute myeloid leukemia (CEBPA-mutated) who cannot tolerate strong chemotherapy. The goal is to see if this treatment can achieve remission and prevent the cancer from returning. Participants will receive two cycles of induction therapy, and if they respond well, up to four more cycles of consolidation therapy, with regular monitoring for side effects and disease status.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • The First Affiliated Hospital of Soochow University

    RECRUITING

    Suzhou, Jiangsu, 215006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.